Ex vivo machine perfusion for renal graft preservation

JM Kaths, A Paul, LA Robinson, M Selzner - Transplantation Reviews, 2018 - Elsevier
Kidney transplantation is the treatment of choice for end-stage renal disease. Despite its
superiority over dialysis, the persisting organ shortage remains a major drawback. Additional …

Normothermic ex vivo kidney perfusion improves early DCD graft function compared with hypothermic machine perfusion and static cold storage

P Urbanellis, M Hamar, JM Kaths, D Kollmann… - …, 2020 - journals.lww.com
Background. Better preservation strategies for the storage of donation after circulatory death
grafts are essential to improve graft function and to increase the kidney donor pool. We …

[HTML][HTML] Normothermic ex vivo kidney perfusion for graft quality assessment prior to transplantation

JM Kaths, M Hamar, J Echeverri, I Linares… - American Journal of …, 2018 - Elsevier
Normothermic ex vivo kidney perfusion (NEVKP) represents a novel approach for graft
preservation and functional improvement in kidney transplantation. We investigated whether …

Continuous normothermic ex vivo kidney perfusion improves graft function in donation after circulatory death pig kidney transplantation

JM Kaths, J Echeverri, YM Chun, JY Cen… - …, 2017 - journals.lww.com
Background Donation after circulatory death (DCD) is current clinical practice to increase
the donor pool. Deleterious effects on renal graft function are described for hypothermic …

Eight-hour continuous normothermic ex vivo kidney perfusion is a safe preservation technique for kidney transplantation: a new opportunity for the storage …

JM Kaths, J Echeverri, N Goldaracena, KS Louis… - …, 2016 - journals.lww.com
Background Hypothermic kidney storage causes preservation injury and is poorly tolerated
by renal grafts. We investigated whether static cold storage (SCS) can be safely replaced …

Normothermic ex vivo kidney perfusion for the preservation of kidney grafts prior to transplantation

JM Kaths, VN Spetzler, N Goldaracena… - JoVE (Journal of …, 2015 - jove.com
Kidney transplantation has become a well-established treatment option for patients with end-stage
renal failure. The persisting organ shortage remains a serious problem. Therefore, …

Subnormothermic ex vivo liver perfusion is a safe alternative to cold static storage for preserving standard criteria grafts

…, N Goldaracena, J Echiverri, JM Kaths… - Liver …, 2016 - journals.lww.com
We developed a novel technique of subnormothermic ex vivo liver perfusion (SNEVLP) for
the storage of liver grafts before transplantation. To test the safety of SNEVLP for the …

[HTML][HTML] Prolonged warm ischemia time leads to severe renal dysfunction of donation-after-cardiac death kidney grafts

…, D Kollmann, I Linares-Cervantes, JM Kaths… - Scientific Reports, 2021 - nature.com
Kidney transplantation with grafts procured after donation-after-cardiac death (DCD) has led
to an increase in incidence of delayed graft function (DGF). It is thought that the warm …

[HTML][HTML] Achalasia with megaesophagus and tracheal compression in a young patient: A case report

JM Kaths, DB Foltys, U Scheuermann… - International journal of …, 2015 - Elsevier
Introduction Achalasia is one of the most common causes of dysphagia. Typical symptoms
include difficulties in controlling the swallowing process, regurgitation, weight loss, and chest …

[HTML][HTML] Transcriptome analysis of kidney grafts subjected to normothermic ex vivo perfusion demonstrates an enrichment of mitochondrial metabolism genes

P Urbanellis, CM McEvoy, M Škrtic, JM Kaths… - Transplantation …, 2021 - journals.lww.com
Background. Normothermic ex vivo kidney perfusion (NEVKP) has demonstrated superior
outcomes for donation-after-cardiovascular death grafts compared with static cold storage (…