User profiles for J. Murnane

Jennifer Murnane-Rainey

Midland University
Verified email at midlandu.edu
Cited by 668

Telomeres, chromosome instability and cancer

SM Bailey, JP Murnane - Nucleic acids research, 2006 - academic.oup.com
… Similar results were observed with other human tumor cell lines (JP Murnane, unpublished
data). This observation is consistent with other studies demonstrating that cancer cells …

Telomere dysfunction and chromosome instability

JP Murnane - … research/Fundamental and molecular mechanisms of …, 2012 - Elsevier
The ends of chromosomes are composed of a short repeat sequence and associated proteins
that together form a cap, called a telomere, that keeps the ends from appearing as double-…

Telomeres and chromosome instability

JP Murnane - DNA repair, 2006 - Elsevier
Genomic instability has been proposed to play an important role in cancer by accelerating
the accumulation of genetic changes responsible for cancer cell evolution. One mechanism …

Paradigm, methodology and method: Intellectual integrity in consumer scholarship

SLT McGregor, JA Murnane - International journal of consumer …, 2010 - Wiley Online Library
The intellectual integrity, trustworthiness and diversity of consumer scholarship depend on
researchers accounting for the methodological (philosophical) underpinnings of their work. …

Telomere dynamics in an immortal human cell line.

JP Murnane, L Sabatier, BA Marder… - The EMBO journal, 1994 - embopress.org
… (Murnane, 1990), Southern blot analysis was performed by digesting DNA with XbaI,
which cuts 3.0 kb from the telomeric repeat sequences on the end of the chromosome (Murnane

DNA-damage response during mitosis induces whole-chromosome missegregation

SF Bakhoum, L Kabeche, JP Murnane, BI Zaki… - Cancer discovery, 2014 - AACR
Many cancers display both structural (s-CIN) and numerical (w-CIN) chromosomal instabilities.
Defective chromosome segregation during mitosis has been shown to cause DNA …

The loss of a single telomere can result in instability of multiple chromosomes in a human tumor cell line

L Sabatier, M Ricoul, G Pottier, JP Murnane - Molecular cancer research, 2005 - AACR
Spontaneous telomere loss has been proposed as an important mechanism for initiating the
chromosome instability commonly found in cancer cells. We have previously shown that …

[HTML][HTML] Mechanisms of telomere loss and their consequences for chromosome instability

K Muraki, K Nyhan, L Han, JP Murnane - Frontiers in oncology, 2012 - frontiersin.org
The ends of chromosomes in mammals, called telomeres, are composed of a 6-bp repeat
sequence, TTAGGG, which is added on by the enzyme telomerase. In combination with a …

Chromosome rearrangements resulting from telomere dysfunction and their role in cancer

JP Murnane, L Sabatier - Bioessays, 2004 - Wiley Online Library
… Fouladi B, Miller D, Sabatier L, Murnane JP. 2000. The relationship between spontaneous
… Bai Y, Murnane JP. 2003. Telomere instability in a human tumor cell line expressing the …

A return on investment evaluation of the Citibank, NA, Health Management Program

…, RZ Goetzel, RI Cantor, J Murnane… - American Journal of …, 1999 - journals.sagepub.com
Objectives. Citibank, NA, initiated a comprehensive health, demand, and disease management
program in 1994, using program services offered by Healthtrac, Inc., of Menlo Park, …