User profiles for J. Nainys

Juozas Nainys

Vilnius University
Verified email at bti.vu.lt
Cited by 3904

[PDF][PDF] Single-cell map of diverse immune phenotypes in the breast tumor microenvironment

…, AE Cornish, C Konopacki, S Prabhakaran, J Nainys… - Cell, 2018 - cell.com
Knowledge of immune cell phenotypes in the tumor microenvironment is essential for
understanding mechanisms of cancer progression and immunotherapy response. We profiled …

[PDF][PDF] Recovering gene interactions from single-cell data using data diffusion

D Van Dijk, R Sharma, J Nainys, K Yim, P Kathail… - Cell, 2018 - cell.com
Single-cell RNA sequencing technologies suffer from many sources of technical noise,
including under-sampling of mRNA molecules, often termed "dropout," which can severely …

Single-cell barcoding and sequencing using droplet microfluidics

R Zilionis, J Nainys, A Veres, V Savova, D Zemmour… - Nature protocols, 2017 - nature.com
Single-cell RNA sequencing has recently emerged as a powerful tool for mapping cellular
heterogeneity in diseased and healthy tissues, yet high-throughput methods are needed for …

MAGIC: A diffusion-based imputation method reveals gene-gene interactions in single-cell RNA-sequencing data

D Dijk, J Nainys, R Sharma, P Kaithail, AJ Carr… - BioRxiv, 2017 - biorxiv.org
… where the entry A(i, j) represents the edge weight between cells i and j. We create a Markov
… t (i,j) represents the probability that a random walk of length t starting at cell i will reach cell j (…

Multi-omics at single-cell resolution: comparison of experimental and data fusion approaches

K Leonavicius, J Nainys, D Kuciauskas… - Current opinion in …, 2019 - Elsevier
Highlights • Sequencing, mass spectrometry and microscopy are common techniques in
single-cell biology. • Microfluidic single-cell RNA-Seq techniques have created a need for …

[HTML][HTML] Generation in yeast of recombinant virus-like particles of porcine circovirus type 2 capsid protein and their use for a serologic assay and development of …

J Nainys, R Lasickiene, R Petraityte-Burneikiene… - BMC …, 2014 - Springer
Background Porcine circovirus type 2 (PCV2) is considered to be an important emerging
pathogen associated with a number of different syndromes and diseases in pigs known as …

Purification of recombinant virus-like particles of porcine circovirus type 2 capsid protein using ion-exchange monolith chromatography

M Zaveckas, S Snipaitis, H Pesliakas, J Nainys… - … of Chromatography B, 2015 - Elsevier
Diseases associated with porcine circovirus type 2 (PCV2) infection are having a severe
economic impact on swine-producing countries. The PCV2 capsid (Cap) protein expressed in …

[HTML][HTML] Identification of Two Novel Members of the Tentative Genus Wukipolyomavirus in Wild Rodents

J Nainys, A Timinskas, J Schneider, RG Ulrich… - PloS one, 2015 - journals.plos.org
Two novel polyomaviruses (PyVs) were identified in kidney and chest-cavity fluid samples
of wild bank voles (Myodes glareolus) and common voles (Microtus arvalis) collected in …

[HTML][HTML] Isolation and Characterization of vB_ArS-ArV2 – First Arthrobacter sp. Infecting Bacteriophage with Completely Sequenced Genome

…, L Truncaitė, A Zajančkauskaitė, J Staniulis, J Nainys… - PLoS …, 2014 - journals.plos.org
This is the first report on a complete genome sequence and biological characterization of
the phage that infects Arthrobacter. A novel virus vB_ArS-ArV2 (ArV2) was isolated from soil …

Molecular analysis of Arthrobacter myovirus vB_ArtM-ArV1: we blame it on the tail

…, L Truncaitė, A Zajančkauskaitė, J Nainys… - Journal of …, 2017 - Am Soc Microbiol
This is the first report on a myophage that infects Arthrobacter . A novel virus, vB_ArtM-ArV1 (ArV1),
was isolated from soil using Arthrobacter sp. strain 68b for phage propagation. …