Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …

Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic variants …

Middle East respiratory syndrome coronavirus (MERS-CoV) is a lineage C betacoronavirus
that since its emergence in 2012 has caused outbreaks in human populations with case-…

HKU1 is a human betacoronavirus that causes mild yet prevalent respiratory disease 1 , and
is related to the zoonotic SARS 2 and MERS 3 betacoronaviruses, which have high fatality …

… Pallesen, J. et al. Immunogenicity and structures of a rationally designed prefusion MERS-CoV
spike antigen… J Gen Physiol 136, 585–592, https://doi.org/10.1085/jgp.201010508 (2010). …

A Brownian machine, a tiny device buffeted by the random motions of molecules in the
environment, is capable of exploiting these thermal motions for many of the conformational …

For many enveloped viruses, binding to a receptor(s) on a host cell acts as the first step in a
series of events culminating in fusion with the host cell membrane and transfer of genetic …

Broadly neutralizing antibodies against highly variable pathogens have stimulated the
design of vaccines and therapeutics. We report the use of diverse camelid single-domain …

Antibodies are promising post-exposure therapies against emerging viruses, but which
antibody features and in vitro assays best forecast protection are unclear. Our international …

Genetic and environmental components as well as their interaction contribute to the risk of
schizophrenia, making it highly relevant to include environmental factors in genetic studies of …