Procaspase-3 overexpression in cancer: a paradoxical observation with therapeutic potential
MW Boudreau, J Peh, PJ Hergenrother - ACS chemical biology, 2019 - ACS Publications
Many anticancer strategies rely on the promotion of apoptosis in cancer cells as a means to
shrink tumors. Crucial for apoptotic function are executioner caspases, most notably caspase…
shrink tumors. Crucial for apoptotic function are executioner caspases, most notably caspase…
[HTML][HTML] Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly
…, C Liang, B Kerouanton, JC Francisco, JH Peh… - Nature …, 2020 - nature.com
The emergence of small open reading frame (sORF)-encoded peptides (SEPs) is rapidly
expanding the known proteome at the lower end of the size distribution. Here, we show that the …
expanding the known proteome at the lower end of the size distribution. Here, we show that the …
[PDF][PDF] Bump-and-hole engineering identifies specific substrates of glycosyltransferases in living cells
Studying posttranslational modifications classically relies on experimental strategies that
oversimplify the complex biosynthetic machineries of living cells. Protein glycosylation …
oversimplify the complex biosynthetic machineries of living cells. Protein glycosylation …
Targeting toxic RNAs that cause myotonic dystrophy type 1 (DM1) with a bisamidinium inhibitor
A working hypothesis for the pathogenesis of myotonic dystrophy type 1 (DM1) involves the
aberrant sequestration of an alternative splicing regulator, MBNL1, by expanded CUG …
aberrant sequestration of an alternative splicing regulator, MBNL1, by expanded CUG …
[HTML][HTML] Augmenting the post-transplantation growth and survivorship of juvenile scleractinian corals via nutritional enhancement
Size-dependant mortality influences the recolonization success of juvenile corals transplanted
for reef restoration and assisting juvenile corals attain a refuge size would thus improve …
for reef restoration and assisting juvenile corals attain a refuge size would thus improve …
Early childhood teacher research and social-emotional learning: Implications for the development of culturally sensitive curriculum in Singapore
Teacher research has been promoted as a context-relevant approach to improving children’s
learning experiences in early childhood settings. In this article, we focus on social-…
learning experiences in early childhood settings. In this article, we focus on social-…
Standard protocol for the dominant lethal test on male mice set up by the work group “dominant lethal mutations of the ad hoc Committee Chemogenetics”
…, J Kratochvilova, R Lang, D Lorke, D Müller, J Peh… - Archives of …, 1978 - Springer
The members of the work group “Dominant Lethal Mutations of the ad hoc Committee
Chemogenetics” jointly carried out experimental studies in the period from November 1972 until …
Chemogenetics” jointly carried out experimental studies in the period from November 1972 until …
Public health impact of mass sporting and cultural events in a rising COVID-19 prevalence in England
A subset of events within the UK Government Events Research Programme (ERP), developed
to examine the risk of transmission of COVID-19 from attendance at events, was examined …
to examine the risk of transmission of COVID-19 from attendance at events, was examined …
A real time simulation optimization framework for vessel collision avoidance and the case of singapore strait
G Pedrielli, Y Xing, JH Peh, KW Koh… - IEEE Transactions on …, 2019 - ieeexplore.ieee.org
Safety is a primary concern for the various transport means. For sea transport, this includes
various aspects like human safety at sea and at port, and also environmental safety and …
various aspects like human safety at sea and at port, and also environmental safety and …
A prevalence study of errors in opioid prescribing in a large teaching hospital
…, S Childs, T Hucker, D Krikos, J Peh… - … journal of clinical …, 2011 - Wiley Online Library
Aim: In 2007, the National Patient Safety Agency performed a study demonstrating that errors
in prescribing led to nearly 12,000 adverse clinical incidents a year. The following year, …
in prescribing led to nearly 12,000 adverse clinical incidents a year. The following year, …