Why have aggregative multicellular organisms stayed simple?
Multicellularity has evolved numerous times across the tree of life. One of the most fundamental
distinctions among multicellular organisms is their developmental mode: whether they …
distinctions among multicellular organisms is their developmental mode: whether they …
[HTML][HTML] Experimental evolution of an alternating uni- and multicellular life cycle in Chlamydomonas reinhardtii
WC Ratcliff, MD Herron, K Howell, JT Pentz… - Nature …, 2013 - nature.com
The transition to multicellularity enabled the evolution of large, complex organisms, but early
steps in this transition remain poorly understood. Here we show that multicellular complexity…
steps in this transition remain poorly understood. Here we show that multicellular complexity…
[HTML][HTML] Killing by Type VI secretion drives genetic phase separation and correlates with increased cooperation
By nature of their small size, dense growth and frequent need for extracellular metabolism,
microbes face persistent public goods dilemmas. Genetic assortment is the only general …
microbes face persistent public goods dilemmas. Genetic assortment is the only general …
Interventions to promote oral medication adherence in the pediatric chronic illness population: a systematic review from the Children's Oncology Group
…, A Lloyd, L Petrando, J Pentz… - Journal of Pediatric …, 2019 - journals.sagepub.com
Pediatric oncology protocols frequently include multiple oral medications administered at
varied dosing schedules, often for prolonged periods of time. Nonadherence to protocol-…
varied dosing schedules, often for prolonged periods of time. Nonadherence to protocol-…
Cellular organization in lab-evolved and extant multicellular species obeys a maximum entropy law
The prevalence of multicellular organisms is due in part to their ability to form complex structures.
How cells pack in these structures is a fundamental biophysical issue, underlying their …
How cells pack in these structures is a fundamental biophysical issue, underlying their …
Cellular packing, mechanical stress and the evolution of multicellularity
S Jacobeen, JT Pentz, EC Graba, CG Brandys… - Nature physics, 2018 - nature.com
The evolution of multicellularity set the stage for sustained increases in organismal complexity
1 , 2 , 3 , 4 – 5 . However, a fundamental aspect of this transition remains largely unknown: …
1 , 2 , 3 , 4 – 5 . However, a fundamental aspect of this transition remains largely unknown: …
[PDF][PDF] Ecological advantages and evolutionary limitations of aggregative multicellular development
All multicellular organisms develop through one of two basic routes: they either aggregate
from free-living cells, creating potentially chimeric multicellular collectives, or they develop …
from free-living cells, creating potentially chimeric multicellular collectives, or they develop …
TEMPO AND MODE OF MULTICELLULAR ADAPTATION IN EXPERIMENTALLY EVOLVED SACCHAROMYCES CEREVISIAE
WC Ratcliff, JT Pentz, M Travisano - Evolution, 2013 - academic.oup.com
Multicellular complexity is a central topic in biology, but the evolutionary processes underlying
its origin are difficult to study and remain poorly understood. Here we use experimental …
its origin are difficult to study and remain poorly understood. Here we use experimental …
Evolutionary consequences of nascent multicellular life cycles
A key step in the evolutionary transition to multicellularity is the origin of multicellular groups
as biological individuals capable of adaptation. Comparative work, supported by theory, …
as biological individuals capable of adaptation. Comparative work, supported by theory, …
Physician pregnancy: male and female colleagues' attitudes.
…, KN Franco, SG Jurs, JE Pentz - Journal of the …, 1992 - europepmc.org
A survey questionnaire was mailed to residents and faculty at a midwestern medical school
to assess male and female attitudes toward colleagues' pregnancies. A total of 67%(N= 97) …
to assess male and female attitudes toward colleagues' pregnancies. A total of 67%(N= 97) …