Changes in membrane voltage brought about by ion fluxes through voltage and transmitter-gated
channels represent the basis of neural activity. As such, electrochemical gradients …

Status epilepticus is a life-threatening neurological emergency that affects both adults and
children. Approximately 36% of episodes of status epilepticus do not respond to the current …

… Author links open overlay panel Joseph V Raimondo 1 , Blake A … JV Raimondo, L. Kay,
TJ Ellender, CJ Akerman … Nevian, J. Wortel, MP Dekker, HD Mansvelder, A. van Ooyen, RM …

Optogenetic silencing using light-driven ion fluxes permits rapid and effective inhibition of
neural activity. Using rodent hippocampal neurons, we found that silencing activity with a …

The primary objective of the gravity recovery and climate experiment followon (GRACE-FO)
satellite mission, due for launch in August 2017, is to continue the GRACE time series of …

Epileptic seizures are characterized by periods of hypersynchronous, hyperexcitability
within brain networks. Most seizures involve two stages: an initial tonic phase, followed by a …

The present study, along with some recent studies, suggests that there is an organic link
between the amount of dialysis a patient receives and his/her nutritional status. The latter, as …

Status epilepticus is defined as a state of unrelenting seizure activity. Generalized convulsive
status epilepticus is associated with a rapidly rising mortality rate, and thus constitutes a …

Seizure-induced release of the neuromodulator adenosine is a potent endogenous
anticonvulsant mechanism, which limits the extension of seizures and mediates seizure arrest. For …

Within the nervous system, intracellular Cl − and pH regulate fundamental processes including
cell proliferation, metabolism, synaptic transmission, and network excitability. Cl − and pH …