m6A in mRNA: an ancient mechanism for fine-tuning gene expression
JY Roignant, M Soller - Trends in Genetics, 2017 - cell.com
Modifications in mRNA constitute ancient mechanisms to regulate gene expression post-transcriptionally.
N 6 -methyladenosine (m 6 A) is the most prominent mRNA modification, and …
N 6 -methyladenosine (m 6 A) is the most prominent mRNA modification, and …
[HTML][HTML] Pattern formation in the Drosophila eye disc
JY Roignant, JE Treisman - The International journal of …, 2009 - ncbi.nlm.nih.gov
Differentiation of the Drosophila compound eye from the eye imaginal disc is a progressive
process: columns of cells successively differentiate in a posterior to anterior sequence, …
process: columns of cells successively differentiate in a posterior to anterior sequence, …
[HTML][HTML] Anything but ordinary–emerging splicing mechanisms in eukaryotic gene regulation
NH Gehring, JY Roignant - Trends in Genetics, 2021 - cell.com
Splicing of precursor mRNAs (pre-mRNA) is an important step during eukaryotic gene
expression. The identification of the actual splice sites and the proper removal of introns are …
expression. The identification of the actual splice sites and the proper removal of introns are …
m6A modulates neuronal functions and sex determination in Drosophila
…, MA Andrade-Navarro, B Poeck, M Helm, JY Roignant - Nature, 2016 - nature.com
N 6 -methyladenosine RNA (m 6 A) is a prevalent messenger RNA modification in vertebrates.
Although its functions in the regulation of post-transcriptional gene expression are …
Although its functions in the regulation of post-transcriptional gene expression are …
Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl (2) d
… Center and the Vienna Drosophila Resource Center for fly reagents, the Drosophila Genomics
Resource Center at Indiana University for plasmids, members of the Bühler and Roignant …
Resource Center at Indiana University for plasmids, members of the Bühler and Roignant …
Absence of transitive and systemic pathways allows cell-specific and isoform-specific RNAi in Drosophila
JY Roignant, C Carré, B Mugat, D Szymczak… - Rna, 2003 - rnajournal.cshlp.org
RNA interference (RNAi) designates the multistep process by which double-stranded RNA
induces the silencing of homologous endogenous genes. Some aspects of RNAi appear to …
induces the silencing of homologous endogenous genes. Some aspects of RNAi appear to …
[HTML][HTML] Hakai is required for stabilization of core components of the m6A mRNA methylation machinery
N 6 -methyladenosine (m 6 A) is the most abundant internal modification on mRNA which
influences most steps of mRNA metabolism and is involved in several biological functions. The …
influences most steps of mRNA metabolism and is involved in several biological functions. The …
The developmental proteome of Drosophila melanogaster
…, D Kappei, B Altenhein, JY Roignant… - Genome …, 2017 - genome.cshlp.org
Drosophila melanogaster is a widely used genetic model organism in developmental
biology. While this model organism has been intensively studied at the RNA level, a …
biology. While this model organism has been intensively studied at the RNA level, a …
Ythdf is a N6‐methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila
…, A Quattrone, A Soldano, JY Roignant - The EMBO …, 2021 - embopress.org
… Vienna Drosophila Resource Center and the Drosophila Genomics Resource Center at
Indiana University for stocks, plasmids and cell lines; members of the Quattrone and Roignant …
Indiana University for stocks, plasmids and cell lines; members of the Quattrone and Roignant …
[HTML][HTML] Exon junction complex subunits are required to splice Drosophila MAP kinase, a large heterochromatic gene
JY Roignant, JE Treisman - Cell, 2010 - cell.com
The exon junction complex (EJC) is assembled on spliced mRNAs upstream of exon-exon
junctions and can regulate their subsequent translation, localization, or degradation. We …
junctions and can regulate their subsequent translation, localization, or degradation. We …