User profiles for J. Schacherer

Joseph Schacherer

University of Strasbourg
Verified email at unistra.fr
Cited by 4368

[HTML][HTML] Genome evolution across 1,011 Saccharomyces cerevisiae isolates

…, A Lemainque, P Wincker, G Liti, J Schacherer - Nature, 2018 - nature.com
Large-scale population genomic surveys are essential to explore the phenotypic diversity of
natural populations. Here we report the whole-genome sequencing and phenotyping of …

Mitochondrial genome evolution in yeasts: an all-encompassing view

KC Freel, A Friedrich, J Schacherer - FEMS yeast research, 2015 - academic.oup.com
Mitochondria are important organelles that harbor their own genomes encoding a key set of
proteins that ensure respiration and provide the eukaryotic cell with energy. Recent …

Comprehensive polymorphism survey elucidates population structure of Saccharomyces cerevisiae

J Schacherer, JA Shapiro, DM Ruderfer, L Kruglyak - Nature, 2009 - nature.com
… Yeast strains were obtained from a number of laboratories: J. Fay (Washington University), …
We are grateful to all the researchers and institutions, and especially J. Fay, for sharing yeast …

[HTML][HTML] Comprehensive survey of condition-specific reproductive isolation reveals genetic incompatibility in yeast

J Hou, A Friedrich, JS Gounot, J Schacherer - Nature communications, 2015 - nature.com
Genetic variation within a species could cause negative epistasis leading to reduced hybrid
fitness and post-zygotic reproductive isolation. Recent studies in yeasts revealed …

Brettanomyces bruxellensis: Overview of the genetic and phenotypic diversity of an anthropized yeast

…, C Miot‐Sertier, J Schacherer… - Molecular …, 2023 - Wiley Online Library
Human‐associated microorganisms are ideal models to study the impact of environmental
changes on species evolution and adaptation because of their small genome, short …

[HTML][HTML] Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae

…, E Kornobis, J Li, Z Miao, L Tattini, J Schacherer… - Nature Genetics, 2023 - nature.com
Pangenomes provide access to an accurate representation of the genetic diversity of
species, both in terms of sequence polymorphisms and structural variants (SVs). Here we …

Genome-wide detection of polymorphisms at nucleotide resolution with a single DNA microarray

D Gresham, DM Ruderfer, SC Pratt, J Schacherer… - Science, 2006 - science.org
A central challenge of genomics is to detect, simply and inexpensively, all differences in
sequence among the genomes of individual members of a species. We devised a system to …

de novo assembly and population genomic survey of natural yeast isolates with the Oxford Nanopore MinION sequencer

…, S Engelen, P Wincker, J Schacherer… - …, 2017 - academic.oup.com
Background: Oxford Nanopore Technologies Ltd (Oxford, UK) have recently commercialized
MinION, a small single-molecule nanopore sequencer, that offers the possibility of …

[PDF][PDF] Chromosomal rearrangements as a major mechanism in the onset of reproductive isolation in Saccharomyces cerevisiae

J Hou, A Friedrich, J de Montigny, J Schacherer - Current Biology, 2014 - cell.com
… A majority-rule consensus tree of the surveyed strains was built based on the 101,343
segregating sites identified by Schacherer et al. [3]. For strains that were not represented in the …

Pichia sorbitophila, an Interspecies Yeast Hybrid, Reveals Early Steps of Genome Resolution After Polyploidization

…, A Sarkar, G Savel, J Schacherer… - G3: Genes …, 2012 - academic.oup.com
Polyploidization is an important process in the evolution of eukaryotic genomes, but
ensuing molecular mechanisms remain to be clarified. Autopolyploidization or whole-genome …