Correspondence to S. Bacchetti. research in this field may render the information rapidly
outdated, we hope that the present survey of over 3500 tumour and control samples will aid …

… We are grateful to Silvia Bacchetti for insightful comments on and critical reading of the
manuscript and to Brittney-Shea Herbert and Ruben Ramirez, members of the Shay-Wright lab, …

Telomere dynamics are a critical component of both aging and cancer. Telomeres progressively
shorten in almost all dividing cells and most human cells do not express or maintain …

Normal human cells undergo a finite number of cell divisions and ultimately enter a nondividing
state called replicative senescence. It has been proposed that telomere shortening is the …

… Scearce and J. Regoeczi for maintenance and growth of cells; J. McConnell, A. Gazdar, P. …
Minna, and J. Watson for critically reviewing the manuscrpt. Supported by Geron Corporation, …

… Special debts of gratitude are due to the following: My companion, Vicki Citron, and my
daughters, Tamar and Hannah Shay, have never compromised on the standards they have …

… Shay, Joseph Leo, 1942– Ternary chalcopyrite semiconductors growth, electronic properties,
and applications. (International series of monographs in the science of the solid state, v. 7) …

Most normal mammalian cells have a finite lifespan 1 , thought to constitute a protective
mechanism against unlimited proliferation 2 , 3 , 4 . This phenomenon, called senescence, is …

… function is as an anticancer mechanism [Wright and Shay, 19951. In brief, the number of cell
… needed for maintenancehepair purposes [Wright and Shay, 19951. Sufficient numbers of …

… IMR90 (ATCC) and B] fibroblasts (obtained from J. Smith, Houston) were culturedin DMEM:M199
(… Lin, J.-H., Wang, M., Andrews, WH, Wydro, R. & Morser, J. Expression efficiency of the …