User profiles for J. Starkova
 | Júlia StarkováCLIP, Second Faculty of Medicine, Charles University, Prague Verified email at lfmotol.cuni.cz Cited by 1036 |
[HTML][HTML] Genomic landscape of pediatric B-other acute lymphoblastic leukemia in a consecutive European cohort
…, A Musilova, K Fiser, M Slamova, J Starkova… - …, 2019 - ncbi.nlm.nih.gov
Novel biological subtypes and clinically important genetic aberrations (druggable lesions,
prognostic factors) have been described in B-other acute lymphoblastic leukemia (ALL) during …
prognostic factors) have been described in B-other acute lymphoblastic leukemia (ALL) during …
[HTML][HTML] Characterization of leukemias with ETV6-ABL1 fusion
…, K Marshall, OA Haas, J Starkova, J Stuchly… - …, 2016 - ncbi.nlm.nih.gov
To characterize the incidence, clinical features and genetics of ETV6-ABL1 leukemias,
representing targetable kinase-activating lesions, we analyzed 44 new and published cases of …
representing targetable kinase-activating lesions, we analyzed 44 new and published cases of …
ETV6/RUNX1 (TEL/AML1) is a frequent prenatal first hit in childhood leukemia
We read with interest the report by Lausten-Thomsen et al in this issue of Blood. 1 The study
challenges the previous report by Mori et al describing 1% frequency of TEL/AML1 (ETV6/…
challenges the previous report by Mori et al describing 1% frequency of TEL/AML1 (ETV6/…
Targeting amino acid metabolism in cancer
L Safrhansova, K Hlozkova, J Starkova - International review of cell and …, 2022 - Elsevier
Metabolic rewiring is a characteristic hallmark of cancer cells. This phenomenon sustains
uncontrolled proliferation and resistance to apoptosis by increasing nutrients and energy …
uncontrolled proliferation and resistance to apoptosis by increasing nutrients and energy …
[HTML][HTML] Human DNA-damage-inducible 2 protein is structurally and functionally distinct from its yeast ortholog
…, J Belza, J Brynda, P Šácha, M Hubálek, J Starková… - Scientific reports, 2016 - nature.com
Although Ddi1-like proteins are conserved among eukaryotes, their biological functions
remain poorly characterized. Yeast Ddi1 has been implicated in cell cycle regulation, DNA-…
remain poorly characterized. Yeast Ddi1 has been implicated in cell cycle regulation, DNA-…
A high-resolution structure of ligand-free human glutamate carboxypeptidase II
…, J Starkova, J Konvalinka, J Lubkowski - … Section F: Structural …, 2007 - scripts.iucr.org
Human glutamate carboxypeptidase II (GCPII; EC 3.4.17.21) is an established marker for
prostate-cancer diagnosis as well as a candidate therapeutic target for the treatment of diverse …
prostate-cancer diagnosis as well as a candidate therapeutic target for the treatment of diverse …
Efficient and versatile one-step affinity purification of in vivo biotinylated proteins: expression, characterization and structure analysis of recombinant human glutamate …
…, J Starkova, J Lubkowski, J Konvalinka - Protein expression and …, 2012 - Elsevier
Affinity purification is a useful approach for purification of recombinant proteins. Eukaryotic
expression systems have become more frequently used at the expense of prokaryotic systems …
expression systems have become more frequently used at the expense of prokaryotic systems …
CD2-positive B-cell precursor acute lymphoblastic leukemia with an early switch to the monocytic lineage
L Slamova, J Starkova, E Fronkova, M Zaliova… - Leukemia, 2014 - nature.com
Switches from the lymphoid to myeloid lineage during B-cell precursor acute lymphoblastic
leukemia (BCP-ALL) treatment are considered rare and thus far have been detected in MLL-…
leukemia (BCP-ALL) treatment are considered rare and thus far have been detected in MLL-…
[HTML][HTML] ERG deletions in childhood acute lymphoblastic leukemia with DUX4 rearrangements are mostly polyclonal, prognostically relevant and their detection rate …
…, E Mejstrikova, J Starkova, J Zuna, J Stary, J Trka - …, 2019 - ncbi.nlm.nih.gov
… Similarly to other recurrent deletions in BCP-ALL, ERGdel is thought to represent a result
of illegitimate RAG1/RAG2-mediated V-(D)-J recombination. This theory is strongly supported …
of illegitimate RAG1/RAG2-mediated V-(D)-J recombination. This theory is strongly supported …
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery
…, P Sacha, J Starková, J Brynda… - Journal of medicinal …, 2021 - ACS Publications
Cryptococcosis is an invasive infection that accounts for 15% of AIDS-related fatalities. Still,
treating cryptococcosis remains a significant challenge due to the poor availability of …
treating cryptococcosis remains a significant challenge due to the poor availability of …