Interactions between respiratory viruses during infection affect transmission dynamics and
clinical outcomes. To identify and characterize virus–virus interactions at the cellular level, we …

Human respiratory syncytial virus (RSV) causes severe respiratory illness in children and
the elderly. Here, using cryogenic electron microscopy and tomography combined with …

Weibel-Palade bodies (WPBs) are secretory granules that contain von Willebrand factor
and P-selectin, molecules that regulate hemostasis and inflammation, respectively. The …

Di‐monoubiquitination of the FANCI‐FANCD2 (ID2) complex is a central and crucial step for
the repair of DNA interstrand crosslinks via the Fanconi anaemia pathway. While FANCD2 …

Macrobrachium rosenbergii nodavirus (MrNV) is a pathogen of freshwater prawns that
poses a threat to food security and causes significant economic losses in the aquaculture …

The Fanconi anaemia (FA) pathway is a dedicated pathway for the repair of DNA interstrand
crosslinks and is additionally activated in response to other forms of replication stress. A key …

Replication of many positive-sense RNA viruses occurs within intracellular membrane-associated
compartments. These are thought to provide a favourable environment for replication …

The assembly of von Willebrand factor (VWF) into ordered helical tubules within endothelial
Weibel–Palade bodies (WPBs) is required for the efficient deployment of the protein at sites …

Human respiratory syncytial virus (RSV) causes severe respiratory illness in children and the
elderly. Treatments for RSV disease are however limited and efforts to produce an effective …

Over the past five years, electron cryo-microscopy (cryo-EM) has become the most popular
and effective technique in structural biology, due to the hardware and software innovations …