[HTML][HTML] Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance

…, M Mannelin, V Martikkala, J Sundvall… - New England journal …, 2001 - Mass Medical Soc
Background Type 2 diabetes mellitus is increasingly common, primarily because of increases
in the prevalence of a sedentary lifestyle and obesity. Whether type 2 diabetes can be …

Sustained reduction in the incidence of type 2 diabetes by lifestyle intervention: follow-up of the Finnish Diabetes Prevention Study

…, J Sundvall, TT Valle, M Uusitupa, J Tuomilehto - The Lancet, 2006 - thelancet.com
… , M Laakso, A Louheranta, M Paturi, J Sundvall, and TT Valle contributed to data extraction
and revised the manuscript. J Tuomilehto and M Uusitupa are the principal investigators of …

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

…, WM Chen, Y Li, LJ Scott, PA Scheet, J Sundvall… - Nature …, 2008 - nature.com
To identify genetic variants influencing plasma lipid concentrations, we first used genotype
imputation and meta-analysis to combine three genome-wide scans totaling 8,816 individuals …

Common variants at 30 loci contribute to polygenic dyslipidemia

…, AJ Swift, J Kuusisto, RN Bergman, J Sundvall… - Nature …, 2009 - nature.com
Blood low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol
and triglyceride levels are risk factors for cardiovascular disease. To dissect the polygenic …

Physical activity in the prevention of type 2 diabetes: the Finnish diabetes prevention study

…, P Härkönen, J Sundvall, J Tuomilehto… - Diabetes, 2005 - Am Diabetes Assoc
Clinical trials have demonstrated that lifestyle changes can prevent type 2 diabetes, but the
importance of leisure-time physical activity (LTPA) is still unclear. We carried out post hoc …

Meta-analysis of genome-wide association studies in> 80 000 subjects identifies multiple loci for C-reactive protein levels

…, S Ripatti, M Nauck, NL Smith, AV Smith, J Sundvall… - Circulation, 2011 - Am Heart Assoc
Background— C-reactive protein (CRP) is a heritable marker of chronic inflammation that is
strongly associated with cardiovascular disease. We sought to identify genetic variants that …

Prevention of Type II diabetes in subjects with impaired glucose tolerance: the Diabetes Prevention Study (DPS) in Finland Study design and 1-year interim report on …

…, M Mannelin, V Martikkala, M Rastas, J Sundvall… - Diabetologia, 1999 - Springer
Aims/hypothesis. The aim of the Diabetes Prevention Study is to assess the efficacy of an
intensive diet-exercise programme in preventing or delaying Type II (non-insulin-dependent) …

Endotoxemia is associated with an increased risk of incident diabetes

PJ Pussinen, AS Havulinna, M Lehto, J Sundvall… - Diabetes …, 2011 - Am Diabetes Assoc
OBJECTIVE Diabetes is accompanied with a chronic low-grade inflammation, which may in
part be mediated by endotoxins derived from Gram-negative bacteria. RESEARCH DESIGN …

Cross-sectional evaluation of the Finnish Diabetes Risk Score: a tool to identify undetected type 2 diabetes, abnormal glucose tolerance and metabolic syndrome

…, J Lindström, L Saarikoski, J Sundvall… - Diabetes and …, 2005 - journals.sagepub.com
The aim of this study was to assess the performance of the Finnish Diabetes Risk Score as a
screening tool for undetected type 2 diabetes (T2D), abnormal glucose tolerance (AGT) and …

Thirty-five-year trends in cardiovascular risk factors in Finland

…, A Juolevi, S Männistö, J Sundvall… - International journal …, 2010 - academic.oup.com
Background In the late 1960s, coronary heart disease (CHD) mortality among Finnish men
was the highest in the world. From 1972 to 2007, risk factor surveys have been carried out to …