α-Linolenic acid supplementation and conversion to n-3 long-chain polyunsaturated fatty acids in humans

JT Brenna, N Salem Jr, AJ Sinclair… - … leukotrienes and essential …, 2009 - Elsevier
Blood levels of polyunsaturated fatty acids (PUFA) are considered biomarkers of status.
Alpha-linolenic acid, ALA, the plant omega-3, is the dietary precursor for the long-chain omega-3 …

[HTML][HTML] Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide

JT Brenna, B Varamini, RG Jensen… - The American journal of …, 2007 - Elsevier
Concentrations of the long-chain polyunsaturated fatty acids (LCPUFAs) docosahexaenoic
acid (DHA, 22:6n−3) and arachidonic acid (AA, 20:4n−6) in human breast milk are important …

Efficiency of conversion of α-linolenic acid to long chain n-3 fatty acids in man

JT Brenna - Current Opinion in Clinical Nutrition & Metabolic Care, 2002 - journals.lww.com
α-Linolenic acid (18: 3n-3) is the major n-3 (ω3) fatty acid in the human diet. It is derived mainly
from terrestrial plant consumption and it has long been thought that its major biochemical …

[HTML][HTML] Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions

…, JT Brenna, N Chiang, F da Costa Souza, J Dalli… - Progress in lipid …, 2022 - Elsevier
Polyunsaturated fatty acids (PUFAs) are structural components of membrane phospholipids,
and influence cellular function via effects on membrane properties, and also by acting as a …

Dietary fat intakes for pregnant and lactating women

B Koletzko, I Cetin, JT Brenna… - British Journal of …, 2007 - cambridge.org
… Berthold Koletzko and Irene Cetin were asked to coordinate the project and asked J.
Thomas Brenna to join the coordination committee. Based on an initial search and review of the …

High‐precision continuous‐flow isotope ratio mass spectrometry

JT Brenna, TN Corso, HJ Tobias… - Mass spectrometry …, 1997 - Wiley Online Library
Although high‐precision isotope determinations are routine in many areas of natural science,
the instrument principles for their measurements have remained remarkably unchanged …

Saturated Fats and Health: A Reassessment and Proposal for Food-Based Recommendations: JACC State-of-the-Art Review

A Astrup, F Magkos, DM Bier, JT Brenna… - Journal of the American …, 2020 - jacc.org
The recommendation to limit dietary saturated fatty acid (SFA) intake has persisted despite
mounting evidence to the contrary. Most recent meta-analyses of randomized trials and …

[HTML][HTML] The 2015 dietary guidelines advisory committee scientific report: development and major conclusions

…, L Adams-Campbell, CAM Anderson, JT Brenna… - Advances in …, 2016 - Elsevier
The Dietary Guidelines for Americans (DGA) is published every 5 y jointly by the Department
of Health and Human Services (HHS) and the USDA and provides a framework for US-…

The influence of dietary docosahexaenoic acid and arachidonic acid on central nervous system polyunsaturated fatty acid composition

JT Brenna, GY Diau - Prostaglandins, Leukotrienes and Essential Fatty …, 2007 - Elsevier
Numerous studies on perinatal long-chain polyunsaturated fatty acid nutrition have clarified
the influence of dietary docosahexaenoic acid (DHA) and arachidonic acid (ARA) on central …

Highly unsaturated fatty acids in nature: what we know and what we need to learn

CW Twining, JT Brenna, NG Hairston Jr, AS Flecker - Oikos, 2016 - Wiley Online Library
The supply and demand of omega‐3 highly unsaturated fatty acids (ω‐3 HUFA) in natural
ecosystems may lead to resource limitation in a diverse array of animal taxa. Here, we review …