User profiles for J. Zobolas

John Zobolas

UiO
Verified email at medisin.uio.no
Cited by 66

Tutorial on survival modeling with applications to omics data

Z Zhao, J Zobolas, M Zucknick, T Aittokallio - Bioinformatics, 2024 - academic.oup.com
Motivation Identification of genomic, molecular and clinical markers prognostic of patient
survival is important for developing personalized disease prevention, diagnostic and treatment …

CausalTAB: the PSI-MITAB 2.8 updated format for signalling data representation and dissemination

…, P Porras, PD Thomas, V Touré, J Zobolas… - …, 2019 - academic.oup.com
Motivation Combining multiple layers of information underlying biological complexity into a
structured framework represent a challenge in systems biology. A key task is the formalization …

IIb‐RAD‐sequencing coupled with random forest classification indicates regional population structuring and sex‐specific differentiation in salmon lice (Lepeophtheirus …

P Guragain, AS Båtnes, J Zobolas, Y Olsen… - Ecology and …, 2022 - Wiley Online Library
The aquaculture industry has been dealing with salmon lice problems forming serious threats
to salmonid farming. Several treatment approaches have been used to control the parasite…

[HTML][HTML] Boolean function metrics can assist modelers to check and choose logical rules

J Zobolas, PT Monteiro, M Kuiper, Å Flobak - Journal of Theoretical Biology, 2022 - Elsevier
… To make f OR - NOT False , we assign the m activators as False and then we investigate
which logical assignments of the inhibitors { y j } j = 1 k make the last DNF term also False . Out …

CausalBuilder: bringing the MI2CAST causal interaction annotation standard to the curator

V Touré, J Zobolas, M Kuiper, S Vercruysse - Database, 2021 - academic.oup.com
Molecular causal interactions are defined as regulatory connections between biological
components. They are commonly retrieved from biological experiments and can be used for …

Fine tuning a logical model of cancer cells to predict drug synergies: combining manual curation and automated parameterization

Å Flobak, J Zobolas, M Vazquez… - Frontiers in Systems …, 2023 - frontiersin.org
Treatment with combinations of drugs carries great promise for personalized therapy for a
variety of diseases. We have previously shown that synergistic combinations of cancer …

Tutorial: guidelines for survival analysis with omics data

Z Zhao, J Zobolas, M Zucknick, T Aittokallio - arXiv preprint arXiv …, 2023 - arxiv.org
The identification of genomic, molecular and clinical markers predictive of patient survival is
important for developing personalized disease prevention, diagnostic and treatment …

UniBioDicts: unified access to biological dictionaries

J Zobolas, V Touré, M Kuiper, S Vercruysse - Bioinformatics, 2021 - academic.oup.com
We present a set of software packages that provide uniform access to diverse biological
vocabulary resources that are instrumental for current biocuration efforts and tools. The Unified …

VSM-box: general-purpose interface for biocuration and knowledge representation

S Vercruysse, J Zobolas, V Touré, MK Andersen… - 2020 - preprints.org
VSM is a recently introduced method for entering and displaying any type of knowledge, in a
form that is both semantically precise for computation and intuitive for human understanding…

[PDF][PDF] emba: R package for analysis and visualization of biomarkers in boolean model ensembles

J Zobolas, M Kuiper, Å Flobak - Journal of open source software, 2020 - joss.theoj.org
… reference manual in the package website (Zobolas, 2020c). Several analyses using the
emba R package are available in a separate repository (Zobolas, 2020d). Future developments …