Structure-function relationships among RNA-dependent RNA polymerases

KKS Ng, JJ Arnold, CE Cameron - RNA interference, 2008 - Springer
… that is stable enough to undergo catalysis (Arnold and Cameron 2004; Arnold et al. 2004).
In … when an incorrect nucleotide is bound (Arnold and Cameron 2004; Arnold et al. 2004). …

Absorption enhancers in pulmonary protein delivery

A Hussain, JJ Arnold, MA Khan, F Ahsan - Journal of Controlled Release, 2004 - Elsevier
Extensive research efforts have been directed towards the systemic administration of therapeutic
proteins and poorly absorbed macromolecules via various nontraditional, injection-free …

Incorporation fidelity of the viral RNA-dependent RNA polymerase: a kinetic, thermodynamic and structural perspective

C Castro, JJ Arnold, CE Cameron - Virus research, 2005 - Elsevier
Positive-strand RNA viruses exist as a quasi-species due to the incorporation of mutations
into the viral genome during replication by the virus-encoded RNA-dependent RNA …

Are single molecular wires conducting?

LA Bumm, JJ Arnold, MT Cygan, TD Dunbar, TP Burgin… - Science, 1996 - science.org
Molecular wire candidates inserted into “nonconducting” n-dodecanethiol self-assembled
monolayers on Au{111} were probed by scanning tunneling microscopy (STM) and microwave …

Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population

M Vignuzzi, JK Stone, JJ Arnold, CE Cameron… - Nature, 2006 - nature.com
An RNA virus population does not consist of a single genotype; rather, it is an ensemble of
related sequences, termed quasispecies 1 , 2 , 3 , 4 . Quasispecies arise from rapid genomic …

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

S Crotty, D Maag, JJ Arnold, W Zhong, JYN Lau… - Nature medicine, 2000 - nature.com
The ribonucleoside analog ribavirin (1-β-D-ribofuranosyl-1, 2, 4-triazole-3-carboxamide)
shows antiviral activity against a variety of RNA viruses and is used in combination with …

Electron transfer through organic molecules

LA Bumm, JJ Arnold, TD Dunbar… - The Journal of …, 1999 - ACS Publications
Electron transfer through molecular frameworks is central to a wide range of chemical,
physical, and biological processes. We demonstrate a means to measure electronically and to …

Early drusen formation in the normal and aging eye and their relation to age related maculopathy: a clinicopathological study

SH Sarks, JJ Arnold, MC Killingsworth… - British Journal of …, 1999 - bjo.bmj.com
AIM To describe the early formation of drusen and their relation to normal aging changes at
the macula and to the development of age related maculopathy (ARM). METHOD …

The mayo high performance teamwork scale: reliability and validity for evaluating key crew resource management skills

…, WF Dunn, DA Wiegmann, JJ Arnold… - Simulation in …, 2007 - journals.lww.com
Purpose: To develop and evaluate a participant rating scale for assessing high performance
teamwork skills in simulation medicine settings. Methods: In all, 107 participants in crisis …

Reticular pseudodrusen: a risk factor in age-related maculopathy

JJ Arnold, SH Sarks, MC Killingsworth, JP Sarks - Retina, 1995 - journals.lww.com
Background: Reticular pseudodrusen refer to a yellow interlacing network 125 [micro] m to
250 [micro] m wide appearing first in the superior outer macula and then extending …