User profiles for J.W. Pinney
John PinneyImperial College London Verified email at imperial.ac.uk Cited by 3429 |
Short Communication: Cataloguing the HIV Type 1 Human Protein Interaction Network
…, JE Dickerson, JW Pinney… - AIDS research and …, 2008 - liebertpub.com
Although many interactions between HIV-1 and human proteins have been reported in the
scientific literature, no publicly accessible source for efficiently reviewing this information was …
scientific literature, no publicly accessible source for efficiently reviewing this information was …
[HTML][HTML] Protein–protein interactions in virus–host systems
To study virus–host protein interactions, knowledge about viral and host protein architectures
and repertoires, their particular evolutionary mechanisms, and information on relevant …
and repertoires, their particular evolutionary mechanisms, and information on relevant …
[PDF][PDF] Petri Net representations in systems biology
The mathematical structures known as Petri Nets have recently become the focus of much
research effort in both the structural and quantitative analysis of all kinds of biological networks…
research effort in both the structural and quantitative analysis of all kinds of biological networks…
[HTML][HTML] A Unique Dual Activity Amino Acid Hydroxylase in Toxoplasma gondii
EA Gaskell, JE Smith, JW Pinney, DR Westhead… - PloS one, 2009 - journals.plos.org
The genome of the protozoan parasite Toxoplasma gondii was found to contain two genes
encoding tyrosine hydroxylase; that produces l-DOPA. The encoded enzymes metabolize …
encoding tyrosine hydroxylase; that produces l-DOPA. The encoded enzymes metabolize …
Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6
The binding of integrin adhesion receptors to their extracellular matrix ligands controls cell
morphology, movement, survival, and differentiation in various developmental, homeostatic, …
morphology, movement, survival, and differentiation in various developmental, homeostatic, …
[HTML][HTML] Low-complexity regions within protein sequences have position-dependent roles
Background Regions of protein sequences with biased amino acid composition (so-called
Low-Complexity Regions (LCRs)) are abundant in the protein universe. A number of studies …
Low-Complexity Regions (LCRs)) are abundant in the protein universe. A number of studies …
Protein-protein interaction networks and biology—what's the connection?
Analysis of protein-protein interaction networks is an increasingly popular means to infer
biological insight, but is close enough attention being paid to data handling protocols and …
biological insight, but is close enough attention being paid to data handling protocols and …
[HTML][HTML] All duplicates are not equal: the difference between small-scale and genome duplication
Background Genes in populations are in constant flux, being gained through duplication and
occasionally retained or, more frequently, lost from the genome. In this study we compare …
occasionally retained or, more frequently, lost from the genome. In this study we compare …
Arabidopsis Co-expression Tool (ACT): web server tools for microarray-based gene expression analysis
IW Manfield, CH Jen, JW Pinney… - Nucleic acids …, 2006 - academic.oup.com
The Arabidopsis Co-expression Tool, ACT, ranks the genes across a large microarray
dataset according to how closely their expression follows the expression of a query gene. A …
dataset according to how closely their expression follows the expression of a query gene. A …
HIV–host interactions: a map of viral perturbation of the host system
JW Pinney, JE Dickerson, W Fu, BE Sanders-Beer… - Aids, 2009 - journals.lww.com
Since the 1980s, the rapid progression of the HIV/AIDS pandemic has prompted a major
international research effort. As a result, the current knowledge on HIV biology, its evolution, …
international research effort. As a result, the current knowledge on HIV biology, its evolution, …