User profiles for J.W. Pinney

John Pinney

Imperial College London
Verified email at imperial.ac.uk
Cited by 3429

Short Communication: Cataloguing the HIV Type 1 Human Protein Interaction Network

…, JE Dickerson, JW Pinney… - AIDS research and …, 2008 - liebertpub.com
Although many interactions between HIV-1 and human proteins have been reported in the
scientific literature, no publicly accessible source for efficiently reviewing this information was …

[HTML][HTML] Protein–protein interactions in virus–host systems

AF Brito, JW Pinney - Frontiers in microbiology, 2017 - frontiersin.org
To study virus–host protein interactions, knowledge about viral and host protein architectures
and repertoires, their particular evolutionary mechanisms, and information on relevant …

[PDF][PDF] Petri Net representations in systems biology

JW Pinney, DR Westhead, GA McConkey - Biochemical Society …, 2003 - Citeseer
The mathematical structures known as Petri Nets have recently become the focus of much
research effort in both the structural and quantitative analysis of all kinds of biological networks…

[HTML][HTML] A Unique Dual Activity Amino Acid Hydroxylase in Toxoplasma gondii

EA Gaskell, JE Smith, JW Pinney, DR Westhead… - PloS one, 2009 - journals.plos.org
The genome of the protozoan parasite Toxoplasma gondii was found to contain two genes
encoding tyrosine hydroxylase; that produces l-DOPA. The encoded enzymes metabolize …

Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6

…, A Byron, MD Bass, SE Craig, JW Pinney… - Science …, 2009 - science.org
The binding of integrin adhesion receptors to their extracellular matrix ligands controls cell
morphology, movement, survival, and differentiation in various developmental, homeostatic, …

[HTML][HTML] Low-complexity regions within protein sequences have position-dependent roles

A Coletta, JW Pinney, DYW Solís, J Marsh… - BMC systems …, 2010 - Springer
Background Regions of protein sequences with biased amino acid composition (so-called
Low-Complexity Regions (LCRs)) are abundant in the protein universe. A number of studies …

Protein-protein interaction networks and biology—what's the connection?

L Hakes, JW Pinney, DL Robertson, SC Lovell - Nature biotechnology, 2008 - nature.com
Analysis of protein-protein interaction networks is an increasingly popular means to infer
biological insight, but is close enough attention being paid to data handling protocols and …

[HTML][HTML] All duplicates are not equal: the difference between small-scale and genome duplication

L Hakes, JW Pinney, SC Lovell, SG Oliver… - Genome biology, 2007 - Springer
Background Genes in populations are in constant flux, being gained through duplication and
occasionally retained or, more frequently, lost from the genome. In this study we compare …

Arabidopsis Co-expression Tool (ACT): web server tools for microarray-based gene expression analysis

IW Manfield, CH Jen, JW Pinney… - Nucleic acids …, 2006 - academic.oup.com
The Arabidopsis Co-expression Tool, ACT, ranks the genes across a large microarray
dataset according to how closely their expression follows the expression of a query gene. A …

HIV–host interactions: a map of viral perturbation of the host system

JW Pinney, JE Dickerson, W Fu, BE Sanders-Beer… - Aids, 2009 - journals.lww.com
Since the 1980s, the rapid progression of the HIV/AIDS pandemic has prompted a major
international research effort. As a result, the current knowledge on HIV biology, its evolution, …