Aging with a traumatic brain injury: Could behavioral morbidities and endocrine symptoms be influenced by microglial priming?
…, RK Rowe, MM Muccigrosso, JT Reddaway… - Brain, behavior, and …, 2017 - Elsevier
A myriad of factors influence the developmental and aging process and impact health and
life span. Mounting evidence indicates that brain injury, even moderate injury, can lead to …
life span. Mounting evidence indicates that brain injury, even moderate injury, can lead to …
[HTML][HTML] Microglial morphometric analysis: so many options, so little consistency
J Reddaway, PE Richardson, RJ Bevan… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Quantification of microglial activation through morphometric analysis has long been a staple
of the neuroimmunologist’s toolkit. Microglial morphological phenomics can be conducted …
of the neuroimmunologist’s toolkit. Microglial morphological phenomics can be conducted …
Enduring neuroimmunological consequences of developmental experiences: From vulnerability to resilience
J Reddaway, NM Brydges - Molecular and Cellular Neuroscience, 2020 - Elsevier
The immune system is crucial for normal neuronal development and function (neuroimmune
system). Both immune and neuronal systems undergo significant postnatal development …
system). Both immune and neuronal systems undergo significant postnatal development …
Neuroimmunological effects of early life experiences
NM Brydges, J Reddaway - Brain and Neuroscience …, 2020 - journals.sagepub.com
Exposure to adverse experiences during development increases the risk of psychiatric
illness later in life. Growing evidence suggests a role for the neuroimmune system in this …
illness later in life. Growing evidence suggests a role for the neuroimmune system in this …
Complement C3 and C3aR mediate different aspects of emotional behaviours; relevance to risk for psychiatric disorder
…, M Toneva, AI Baloc, AL Moon, J Reddaway… - Brain, Behavior, and …, 2022 - Elsevier
Complement is a key component of the immune system with roles in inflammation and host-defence.
Here we reveal novel functions of complement pathways impacting on emotional …
Here we reveal novel functions of complement pathways impacting on emotional …
ECCO–A new initiative to support early-career researchers in the complement field
Research on the complement system, like most areas of immunology, has seen tremendous
progress over the last decades. Further advances in the complement field will rely on the …
progress over the last decades. Further advances in the complement field will rely on the …
[HTML][HTML] Early-Career Complementologists (ECCO)–Past achievements and future directions
The Early-Career Complementologists (ECCO) is a task force that was established, in close
collaboration with the European Complement Network (ECN) and the International …
collaboration with the European Complement Network (ECN) and the International …
The role of the complement system in associative learning and risk for schizophrenia
J Reddaway - 2022 - orca.cardiff.ac.uk
Schizophrenia and post-traumatic stress disorder are neuropsychiatric disorders which in part
are characterised by impairments in the acquisition and updating of associative memories. …
are characterised by impairments in the acquisition and updating of associative memories. …
Manipulating immune pathways differentially impact emotionality: Dissociable effects of complement C3 and C3aR on learned fear and innate anxiety
…, SA Brain, EL Bush, M Toneva, AL Moon, J Reddaway… - bioRxiv, 2019 - biorxiv.org
Background Recent findings implicate complement, a key component of the immune system,
in healthy brain functioning and risk for psychiatric disorders. Altered emotional function, in …
in healthy brain functioning and risk for psychiatric disorders. Altered emotional function, in …
Differential ability of the dorsal and ventral rat hippocampus to exhibit group I metabotropic glutamate receptor–dependent synaptic and intrinsic plasticity
P Tidball, HV Burn, KL Teh… - Brain and …, 2017 - journals.sagepub.com
Background: The hippocampus is critically involved in learning and memory processes.
Although once considered a relatively homogenous structure, it is now clear that the …
Although once considered a relatively homogenous structure, it is now clear that the …