User profiles for Jackelyn Murray
Jaclyn Kuspiel MurrayAssistant Professor, Mercer University Verified email at mercer.edu Cited by 154 |
Characterization and noncovalent inhibition of the deubiquitinase and deISGylase activity of SARS-CoV-2 papain-like protease
BT Freitas, IA Durie, J Murray, JE Longo… - ACS infectious …, 2020 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for
COVID-19, is a novel human betacoronavirus that is rapidly spreading worldwide. The …
COVID-19, is a novel human betacoronavirus that is rapidly spreading worldwide. The …
[HTML][HTML] Species-agnostic polymeric formulations for inhalable messenger RNA delivery to the lung
Messenger RNA has now been used to vaccinate millions of people. However, the diversity
of pulmonary pathologies, including infections, genetic disorders, asthma and others, …
of pulmonary pathologies, including infections, genetic disorders, asthma and others, …
[HTML][HTML] Treatment of influenza and SARS-CoV-2 infections via mRNA-encoded Cas13a in rodents
Cas13a has been used to target RNA viruses in cell culture, but efficacy has not been
demonstrated in animal models. In this study, we used messenger RNA (mRNA)-encoded Cas13a …
demonstrated in animal models. In this study, we used messenger RNA (mRNA)-encoded Cas13a …
Silver nanotriangle array based LSPR sensor for rapid coronavirus detection
A rapid, portable, and cost-effective method to detect the infection of SARS-CoV-2 is
fundamental toward mitigating the current COVID-19 pandemic. Herein, a human angiotensin-…
fundamental toward mitigating the current COVID-19 pandemic. Herein, a human angiotensin-…
Rapid and quantitative detection of respiratory viruses using surface-enhanced Raman spectroscopy and machine learning
Y Yang, B Xu, J Murray, J Haverstick, X Chen… - Biosensors and …, 2022 - Elsevier
Rapid and sensitive pathogen detection is important for prevention and control of disease.
Here, we report a label-free diagnostic platform that combines surface-enhanced Raman …
Here, we report a label-free diagnostic platform that combines surface-enhanced Raman …
[HTML][HTML] Selinexor, a novel selective inhibitor of nuclear export, reduces SARS-CoV-2 infection and protects the respiratory system in vivo
T Kashyap, J Murray, CJ Walker, H Chang, S Tamir… - Antiviral Research, 2021 - Elsevier
The novel coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is responsible for the recent global pandemic. The …
syndrome coronavirus 2 (SARS-CoV-2) is responsible for the recent global pandemic. The …
Rapid detection of SARS-CoV-2 RNA in human nasopharyngeal specimens using surface-enhanced raman spectroscopy and deep learning algorithms
Y Yang, H Li, L Jones, J Murray, J Haverstick… - Acs …, 2022 - ACS Publications
A rapid and cost-effective method to detect the infection of SARS-CoV-2 is fundamental to
mitigating the current COVID-19 pandemic. Herein, a surface-enhanced Raman spectroscopy (…
mitigating the current COVID-19 pandemic. Herein, a surface-enhanced Raman spectroscopy (…
[HTML][HTML] Probenecid inhibits SARS-CoV-2 replication in vivo and in vitro
Effective vaccines are slowing the COVID-19 pandemic, but SARS-CoV-2 will likely remain
an issue in the future making it important to have therapeutics to treat patients. There are few …
an issue in the future making it important to have therapeutics to treat patients. There are few …
[HTML][HTML] Probenecid inhibits respiratory syncytial virus (RSV) replication
J Murray, HC Bergeron, LP Jones, ZB Reener… - Viruses, 2022 - mdpi.com
RNA viruses like SARS-CoV-2, influenza virus, and respiratory syncytial virus (RSV) are
dependent on host genes for replication. We investigated if probenecid, an FDA-approved and …
dependent on host genes for replication. We investigated if probenecid, an FDA-approved and …
[HTML][HTML] Respiratory syncytial virus (RSV) G protein vaccines with central conserved domain mutations induce CX3C-CX3CR1 blocking antibodies
HC Bergeron, J Murray, AM Nuñez Castrejon… - Viruses, 2021 - mdpi.com
Respiratory syncytial virus (RSV) infection can cause bronchiolitis, pneumonia, morbidity,
and some mortality, primarily in infants and the elderly, for which no vaccine is available. The …
and some mortality, primarily in infants and the elderly, for which no vaccine is available. The …