We report a large multicenter genome-wide association study of Plasmodium falciparum
resistance to artemisinin, the frontline antimalarial drug. Across 15 locations in Southeast Asia, …

We describe an analysis of genome variation in 825 P. falciparum samples from Asia and
Africa that identifies an unusual pattern of parasite population structure at the epicenter of …

Malaria elimination strategies require surveillance of the parasite population for genetic
changes that demand a public health response, such as new forms of drug resistance 1 , 2 . …

Background As the prevalence of artemisinin-resistant Plasmodium falciparum malaria
increases in the Greater Mekong subregion, emerging resistance to partner drugs in artemisinin …

Background Antimalarial resistance is rapidly spreading across parts of southeast Asia where
dihydroartemisinin–piperaquine is used as first-line treatment for Plasmodium falciparum …

The widespread distribution and relapsing nature of Plasmodium vivax infection present
major challenges for the elimination of malaria. To characterize the genetic diversity of this …

The increasing availability of large genomic data sets as well as the advent of Bayesian
phylogenetics facilitates the investigation of phylogenetic incongruence, which can result in the …

A major obstacle to malaria elimination is the great capacity of the parasite and vector
populations to evolve in response to malaria control interventions. The widespread use of …

Background: National Malaria Control Programmes (NMCPs) currently make limited use of
parasite genetic data. We have developed GenRe-Mekong, a platform for genetic …

We describe the MalariaGEN Pf7 data resource, the seventh release of Plasmodium falciparum
genome variation data from the MalariaGEN network. It comprises over 20,000 samples …