Hedgehog signaling requires motile cilia in the sea urchin

JF Warner, AM McCarthy, RL Morris… - Molecular biology and …, 2014 - academic.oup.com
A relatively small number of signaling pathways govern the early patterning processes of
metazoan development. The architectural changes over time to these signaling pathways offer …

[HTML][HTML] Characterization of Morphological and Cellular Events Underlying Oral Regeneration in the Sea Anemone, Nematostella vectensis

…, HT Johnston, K Nedoncelle, JF Warner… - International journal of …, 2015 - mdpi.com
Cnidarians, the extant sister group to bilateria, are well known for their impressive regenerative
capacity. The sea anemone Nematostella vectensis is a well-established system for the …

NvERTx: a gene expression database to compare embryogenesis and regeneration in the sea anemone Nematostella vectensis

JF Warner, V Guerlais, AR Amiel, H Johnston… - …, 2018 - journals.biologists.com
For over a century, researchers have been comparing embryogenesis and regeneration
hoping that lessons learned from embryonic development will unlock hidden regenerative …

[HTML][HTML] Morphological and transcriptional effects of crude oil and dispersant exposure on the marine sponge Cinachyrella alloclada

Y Desplat, JF Warner, EJ Blake, N Vijayan… - Science of The Total …, 2023 - Elsevier
… Author links open overlay panel Yvain Desplat a 1 , Jacob F. Warner b , Emily J. Blake a
2 , Nidhi Vijayan a 3 , Marie Cuvelier a , Patricia Blackwelder a c , Jose V. Lopez a …

Chromosomal-Level Genome Assembly of the Painted Sea Urchin Lytechinus pictus: A Genetically Enabled Model System for Cell Biology and Embryonic …

JF Warner, JW Lord, SA Schreiter… - Genome Biology and …, 2021 - academic.oup.com
The painted urchin Lytechinus pictus is a sea urchin in the family Toxopneustidae and one
of several sea urchin species that are routinely used as an experimental research organism. …

Microinjection, gene knockdown, and CRISPR-mediated gene knock-in in the hard coral, Astrangia poculata

JF Warner, R Besemer, A Schickle, IV Changsut… - bioRxiv, 2023 - biorxiv.org
Cnidarians have become valuable models for understanding many aspects of developmental
biology including the evolution of body plan diversity, novel cell type specification, and …

[HTML][HTML] Contribution of hedgehog signaling to the establishment of left–right asymmetry in the sea urchin

JF Warner, EL Miranda, DR McClay - Developmental biology, 2016 - Elsevier
Most bilaterians exhibit a left–right asymmetric distribution of their internal organs. The sea
urchin larva is notable in this regard since most adult structures are generated from left sided …

[HTML][HTML] Left-right asymmetry in the sea urchin embryo: BMP and the asymmetrical origins of the adult

JF Warner, DC Lyons, DR McClay - 2012 - journals.plos.org
Bilateral animals, including humans and most metazoans, are not perfectly symmetrical.
Some internal structures are distributed asymmetrically to the right or left side. A conserved …

Whole body regeneration deploys a rewired embryonic gene regulatory network logic

H Johnston, JF Warner, AR Amiel, K Nedoncelle… - bioRxiv, 2019 - biorxiv.org
For over a century, researchers have been trying to understand the relationship between
embryogenesis and regeneration. A long-standing hypothesis is that biological processes …

[HTML][HTML] Conditional specification of endomesoderm

DR McClay, JC Croce, JF Warner - Cells & development, 2021 - Elsevier
Early in animal development many cells are conditionally specified based on observations
that those cells can be directed toward alternate fates. The endomesoderm is so named …