Infection with severe acute respiratory syndrome coronavirus 2 associates with diverse
symptoms, which can persist for months. While antiviral antibodies are protective, those targeting …

The mechanisms by which mitochondrial metabolism supports cancer anabolism remain
unclear. Here, we found that genetic and pharmacological inactivation of pyruvate …

Transcription factors are proteins able to bind DNA and induce the transcription of specific
genes. Consequently, they play a pivotal role in multiple cellular pathways and are frequently …

Emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
diminishes the efficacy of vaccines and antiviral monoclonal antibodies. Continued development …

With the aim to design addressable magnetically‐active carbon nanotubes (CNTs) for cancer
treatment, the use of Fe‐filled CNTs (Fe@MWCNTs) as multifunctional scaffolds is reported …

Impaired cellular cholesterol efflux is a key factor in the progression of renal, cardiovascular,
and autoimmune diseases. Here we describe a class of 5-arylnicotinamide compounds, …

In systemic light chain amyloidosis (AL), pathogenic monoclonal immunoglobulin light chains
(LC) form toxic aggregates and amyloid fibrils in target organs. Prompt diagnosis is crucial …

Human aromatase (HA), an enzyme located on the membrane of the endoplasmatic
reticulum, is of crucial biological importance in the biosynthesis of estrogens. High levels of …

The TMPRSS2-ERG gene fusion is the most frequent alteration observed in human prostate
cancer. However, its role in disease progression is still unclear. In this study, we uncover an …

Flap endonucleases (FENs) are nucleic acid hydrolyzing enzymes in charge of excising 5′-small
DNA and RNA fragments (flaps) protruding from nucleic acid structures during the …