The development of clinically viable delivery methods presents one of the greatest challenges
in the therapeutic application of CRISPR/Cas9 mediated genome editing. Here, we report …

The intricate connection between the circadian clock and metabolism remains poorly
understood. We used high temporal resolution metabolite profiling to explore clock regulation of …

Over the last decades, researchers have characterized a set of “clock genes” that drive daily
rhythms in physiology and behavior. This arduous work has yielded results with far-reaching …

Circadian disruption influences metabolic health. Metabolism modulates circadian function.
However, the mechanisms coupling circadian rhythms and metabolism remain poorly …

Oscillations in circadian metabolism are crucial to the well being of organism. Our
understanding of metabolic rhythms has been greatly enhanced by recent advances in high-…

The duper mutation is a recessive mutation that shortens the period length of the circadian
rhythm in Syrian hamsters. These animals show a large phase shift when responding to light …

IKE EVERYONE ELSE who knew Derek Brewer, I feel extremely lucky I to have done so, and
I treasure the memory of all our conversations. In particular, I remember one that prompted …

… His story," Jacqueline," among those here reprinted with many unpublished letters, was
called one of the best pieces of writing that came from the American Expeditionary Forces. The …

The change in women’s roles in recent times has certainly contributed to the change in
female speech styles. Power and dominance which were once considered traits of the male …

In pursuing how fourteenth-century English texts engage with philosophical, intellectual,
and theological questions, the work of Denise N. Baker has powerfully shaped the field of …