User profiles for Jacquelyn M. Roger

Jacquelyn Roger

University of California, San Francisco
Verified email at ucsf.edu
Cited by 83

Transfer RNA genes experience exceptionally elevated mutation rates

BP Thornlow, J Hough, JM Roger… - Proceedings of the …, 2018 - National Acad Sciences
… and M. mulatta, and 15% of human tRNA loci have a low-frequency SNP (Fig. 1). Furthermore,
virtually all active tRNA loci differ at this nucleotide between human and M… We obtained M. …

The case for using mapped exonic non-duplicate reads when reporting RNA-sequencing depth: examples from pediatric cancer datasets

HC Beale, JM Roger, MA Cattle, LT McKay… - …, 2021 - academic.oup.com
Background The reproducibility of gene expression measured by RNA sequencing (RNA-Seq)
is dependent on the sequencing depth. While unmapped or non-exonic reads do not …

Retrospective analysis of wildfire smoke exposure and birth weight outcomes in the San Francisco Bay Area of California

…, E Basilio, T Benmarhnia, J Roger… - Environmental …, 2023 - iopscience.iop.org
… wildfire PM 2.5 exceeded 5 μg m −3 to capture exposure … m −3 ( ß = 0.009; 95% CI: 0.001,
0.017) in the second trimester. The Beta coefficient derived from linear regression for 1 μg m −…

[HTML][HTML] Leveraging electronic health records to identify risk factors for recurrent pregnancy loss across two medical centers: a case-control study

J Roger, F Xie, J Costello, A Tang, J Liu… - Research …, 2023 - ncbi.nlm.nih.gov
Recurrent pregnancy loss (RPL), defined as 2 or more pregnancy losses, affects 5–6% of
ever-pregnant individuals. Approximately half of these cases have no identifiable explanation. …

[HTML][HTML] Leveraging electronic health records and knowledge networks for Alzheimer's disease prediction and sex-specific biological insights

…, KP Rankin, G Cerono, S Miramontes, H Mills, J Roger… - Nature Aging, 2024 - nature.com
Identification of Alzheimer’s disease (AD) onset risk can facilitate interventions before irreversible
disease progression. We demonstrate that electronic health records from the University …

Data-driven longitudinal characterization of neonatal health and morbidity

…, J Roger, AS Tang, AL Chang, M Becker… - Science Translational …, 2023 - science.org
Although prematurity is the single largest cause of death in children under 5 years of age,
the current definition of prematurity, based on gestational age, lacks the precision needed for …

Bottom-up drivers of future fire regimes in western boreal North America

AC Foster, JK Shuman, BM Rogers… - Environmental …, 2022 - iopscience.iop.org
Forest characteristics, structure, and dynamics within the North American boreal region are
heavily influenced by wildfire intensity, severity, and frequency. Increasing temperatures are …

[HTML][HTML] Translational bioinformatics to enable precision medicine for all: elevating equity across molecular, clinical, and digital realms

…, S Woldemariam, J Roger, M Sirota - Yearbook of Medical …, 2022 - thieme-connect.com
Objectives: Over the past few years, challenges from the pandemic have led to an explosion
of data sharing and algorithmic development efforts in the areas of molecular measurements…

Fire as a fundamental ecological process: Research advances and frontiers

…, PE Higuera, J Miesel, BM Rogers… - Journal of …, 2020 - Wiley Online Library
Fire is a powerful ecological and evolutionary force that regulates organismal traits, population
sizes, species interactions, community composition, carbon and nutrient cycling and …

Framework for determining accuracy of RNA sequencing data for gene expression profiling of single samples

HC Beale, JM Roger, MA Cattle, LT McKay, K Learned… - bioRxiv, 2019 - biorxiv.org
Background The accuracy of gene expression as measured by RNA sequencing (RNA-Seq)
is dependent on the amount of sequencing performed. However, some types of reads are …