Although proteins are translated on cytoplasmic ribosomes, many of these proteins play
essential roles in the nucleus, mediating key cellular processes including but not limited to DNA …

Proteins are translated in the cytoplasm, but many need to access the nucleus to perform their
functions. Understanding how these nuclear proteins are transported through the nuclear …

Acyl-coenzyme A thioesterases (Acots) play important cellular roles in mammalian fatty acid
metabolism through modulation of cellular concentrations of activated fatty acyl-CoAs. Acots …

The gene-for-gene mechanism of plant disease resistance involves direct or indirect
recognition of pathogen avirulence (Avr) proteins by plant resistance (R) proteins. Flax rust (…

Dengue virus multifunctional proteins NS3 protease/helicase and NS5 methyltransferase/RNA-dependent
RNA polymerase form part of the viral replication complex and are involved in …

The architectural transcription factor SRY (sex-determining region of the Y chromosome)
plays a key role in sex determination as indicated by the fact that mutations in SRY are …

In vitro, ACE2 translocates to the nucleus to induce SARS-CoV-2 replication. Here, using
digital spatial profiling of lung tissues from SARS-CoV-2-infected golden Syrian hamsters, we …

Classical nuclear localization signals ( cNLSs ), comprising one (monopartite cNLSs ) or
two clusters of basic residues connected by a 10–12 residue linker (bipartite cNLSs ), are …

The structure of solenoid proteins facilitates a higher degree of flexibility than most folded
proteins. In importin-β, a nuclear import factor built from 19 tandem HEAT repeats, flexibility …

Dengue virus NS5 is the most highly conserved amongst the viral non-structural proteins
and is responsible for capping, methylation and replication of the flavivirus RNA genome. …