Background In an era of shifting global agendas and expanded emphasis on non-communicable
diseases and injuries along with communicable diseases, sound evidence on trends …

Importance Accurate and up-to-date estimates on incidence, prevalence, mortality, and
disability-adjusted life-years (burden) of neurological disorders are the backbone of evidence-…

The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a
rules-based synthesis of the available evidence on levels and trends in health outcomes, a …

The formation of precise connections between retina and lateral geniculate nucleus (LGN)
involves the activity-dependent elimination of some synapses, with strengthening and …

Recovery from stroke engages mechanisms of neural plasticity. Here we examine a role for
MHC class I (MHCI) H2-Kb and H2-Db, as well as PirB receptor. These molecules restrict …

During critical periods of development, the brain easily changes in response to environmental
stimuli, but this neural plasticity declines by adulthood. By acutely disrupting paired …

Objectives To identify and assess the evidence for interventions to reduce stigma experienced
by children with disabilities and their families in low‐ and middle‐income settings. …

Mature dentate granule cells in the hippocampus receive input from the entorhinal cortex via
the perforant path in precisely arranged lamina, with medial entorhinal axons innervating …

Synapse pruning is an activity-regulated process needed for proper circuit sculpting in the
developing brain. Major histocompatibility class I (MHCI) molecules are regulated by activity, …

Current evidence suggests that demyelination may be a necessary but not a sufficient condition
for neurologic deficits associated with multiple sclerosis. Axon injury that occurs within …