User profiles for James A. Eddy
James A EddyDirector of Informatics & Biocomputing, Sage Bionetworks Verified email at sagebase.org Cited by 7582 |
[PDF][PDF] The immune landscape of cancer
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising
33 diverse cancer types by utilizing data compiled by TCGA. Across cancer types, we …
33 diverse cancer types by utilizing data compiled by TCGA. Across cancer types, we …
[PDF][PDF] IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior
Anti-inflammatory strategies are proposed to have beneficial effects in Alzheimer's disease.
To explore how anti-inflammatory cytokine signaling affects Aβ pathology, we investigated …
To explore how anti-inflammatory cytokine signaling affects Aβ pathology, we investigated …
[PDF][PDF] GA4GH: International policies and standards for data sharing across genomic research and healthcare
The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical
advances by enabling the responsible sharing of clinical and genomic data through both …
advances by enabling the responsible sharing of clinical and genomic data through both …
[HTML][HTML] Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases
…, CS Younkin, JD Burgess, HS Chai, J Crook, JA Eddy… - Scientific data, 2016 - nature.com
Previous genome-wide association studies (GWAS), conducted by our group and others,
have identified loci that harbor risk variants for neurodegenerative diseases, including …
have identified loci that harbor risk variants for neurodegenerative diseases, including …
[PDF][PDF] Meta-analysis of the Alzheimer's disease human brain transcriptome and functional dissection in mouse models
We present a consensus atlas of the human brain transcriptome in Alzheimer's disease (AD),
based on meta-analysis of differential gene expression in 2,114 postmortem samples. We …
based on meta-analysis of differential gene expression in 2,114 postmortem samples. We …
[HTML][HTML] Reconstruction of genome-scale metabolic models for 126 human tissues using mCADRE
Background Human tissues perform diverse metabolic functions. Mapping out these tissue-specific
functions in genome-scale models will advance our understanding of the metabolic …
functions in genome-scale models will advance our understanding of the metabolic …
[HTML][HTML] Dynamic analysis of integrated signaling, metabolic, and regulatory networks
Extracellular cues affect signaling, metabolic, and regulatory processes to elicit cellular
responses. Although intracellular signaling, metabolic, and regulatory networks are highly …
responses. Although intracellular signaling, metabolic, and regulatory networks are highly …
[HTML][HTML] The immune landscape of cancer
(Immunity 48, 812–830.e1–e14; April 17, 2018) In the originally published version of this
article, the authors neglected to include Younes Mokrab and Aaron M. Newman as co-authors …
article, the authors neglected to include Younes Mokrab and Aaron M. Newman as co-authors …
[PDF][PDF] The influence of significant others on attitudes, subjective norms and intentions regarding dietary supplement use among adolescent athletes
MS Dunn, JM Eddy, MQ Wang, S Nagy… - ADOLESCENCE …, 2001 - libres.uncg.edu
Dietary supplement use has increased significantly over the past decade. The use of
supplements among adolescents seems to be influenced by their beliefs and attitudes. The …
supplements among adolescents seems to be influenced by their beliefs and attitudes. The …
Family and peer influences on smoking behavior among American adolescents: an age trend
…, EC Fitzhugh, RC Westerfield, JM Eddy - Journal of adolescent …, 1995 - Elsevier
PURPOSE:: To study the age trend of family and peer influence on adolescent smoking
behavior using a national sample. METHODS:: Adolescents (N = 6,900), ages 14 through 18 …
behavior using a national sample. METHODS:: Adolescents (N = 6,900), ages 14 through 18 …