Adult Drosophila possess a large number of sensory organs, including large and small bristles
and other types of sensilla, each arising from a single mother cell at particular positions in …

Asymmetric cell division is a general process used in many developmental contexts to
create two differently fated cells from a single progenitor cell. Intrinsic mechanisms like the …

The Drosophila ventral nerve cord has been a central model system for studying the molecular
genetic mechanisms that control CNS development. Studies show that the generation of …

The mammalian Ajuba LIM proteins (Ajuba, LIMD1, and WTIP) are adaptor proteins that
exhibit the potential to communicate cell adhesive events with nuclear responses to remodel …

After invagination of the mesodermal primordium in the gastrulating Drosophila embryo, the
internalized cells migrate in a dorsolateral direction along the overlying ectoderm. This …

The Drosophila embryonic central nervous system develops from sets of progenitor neuroblasts
which segregate from the neuroectoderm during early embryogenesis. Cells within this …

Drosophila is an ideal system for identifying genes that control central nervous system (CNS)
development. Particularly useful tools include molecular markers for subsets of neural …

In Drosophila, most neuronal siblings have different fates (‘A/B’). Here we demonstrate that
mutations in sanpodo, a tropomodulin actin-binding protein homologue, equalize a diverse …

Cellular diversity is a fundamental characteristic of complex organisms, and the Drosophila
CNS has proved an informative paradigm for understanding the mechanisms that create …

The specification of specific and often unique fates to individual cells as a function of their
position within a developing organism is a fundamental process during the development of …