User profiles for James C Vickers
James VickersUniversity of Tasmania Verified email at utas.edu.au Cited by 10856 |
The cause of neuronal degeneration in Alzheimer's disease
Alzheimer's disease is associated with a specific pattern of pathological changes in the
brain that result in neurodegeneration and the progressive development of dementia. …
brain that result in neurodegeneration and the progressive development of dementia. …
Relationship between education and age‐related cognitive decline: A review of recent research
…, NL Saunders, JJ Summers, JC Vickers - …, 2015 - Wiley Online Library
The association between level of educational attainment and cognitive performance is well
studied. People with higher education perform better across a broad range of cognitive tasks. …
studied. People with higher education perform better across a broad range of cognitive tasks. …
Focal demyelination in Alzheimer's disease and transgenic mouse models
We have investigated alterations in myelin associated with Aβ plaques, a major pathological
hallmark of Alzheimer’s disease (AD), in human tissue and relevant transgenic mice models…
hallmark of Alzheimer’s disease (AD), in human tissue and relevant transgenic mice models…
Excitotoxicity in ALS: overstimulation, or overreaction?
Amyotrophic lateral sclerosis (ALS) is an adult onset neurodegenerative disease that results
in motor dysfunction and death, generally from respiratory failure. 90% of ALS cases are …
in motor dysfunction and death, generally from respiratory failure. 90% of ALS cases are …
[HTML][HTML] Redefining the role of metallothionein within the injured brain: extracellular metallothioneins play an important role in the astrocyte-neuron response to injury
…, LD Beazley, MI Chuah, JC Vickers… - Journal of biological …, 2008 - ASBMB
A number of intracellular proteins that are protective after brain injury are classically thought
to exert their effect within the expressing cell. The astrocytic metallothioneins (MT) are one …
to exert their effect within the expressing cell. The astrocytic metallothioneins (MT) are one …
Altered synapses and gliotransmission in Alzheimer's disease and AD model mice
Amyloid-β (Aβ) plaque accumulation in Alzheimer's disease (AD) is associated with
glutamatergic synapse loss, but less is known about its effect on inhibitory synapses. Here, we …
glutamatergic synapse loss, but less is known about its effect on inhibitory synapses. Here, we …
[HTML][HTML] Diffuse axonal injury in brain trauma: insights from alterations in neurofilaments
…, MI Chuah, MTK Kirkcaldie, JC Vickers… - Frontiers in cellular …, 2014 - frontiersin.org
Traumatic brain injury (TBI) from penetrating or closed forces to the cranium can result in a
range of forms of neural damage, which culminate in mortality or impart mild to significant …
range of forms of neural damage, which culminate in mortality or impart mild to significant …
Neurochemical diversity of dystrophic neurites in the early and late stages of Alzheimer's disease
…, CE King, GH McCormack, JC Vickers - Experimental neurology, 1999 - Elsevier
We examined the neurochemical and morphological diversity of abnormal neurites associated
with β-amyloid plaque formation in the early and late stages of Alzheimer's disease. …
with β-amyloid plaque formation in the early and late stages of Alzheimer's disease. …
[HTML][HTML] Delayed plastic responses to anodal tDCS in older adults
…, SJ Kim, GH McCormack, JC Vickers… - Frontiers in aging …, 2014 - frontiersin.org
Despite the abundance of research reporting the neurophysiological and behavioral effects
of transcranial direct current stimulation (tDCS) in healthy young adults and clinical …
of transcranial direct current stimulation (tDCS) in healthy young adults and clinical …
Initial calcium release from intracellular stores followed by calcium dysregulation is linked to secondary axotomy following transient axonal stretch injury
… C, washed with fresh artificial CSF and incubated at 37C for a further 15–20 min prior to
imaging. Images were captured every second using a cooled CCD camera (ORCA, Hamamtsu, …
imaging. Images were captured every second using a cooled CCD camera (ORCA, Hamamtsu, …