User profiles for James C Vickers

James Vickers

University of Tasmania
Verified email at utas.edu.au
Cited by 10856

The cause of neuronal degeneration in Alzheimer's disease

JC Vickers, TC Dickson, PA Adlard, HL Saunders… - Progress in …, 2000 - Elsevier
Alzheimer's disease is associated with a specific pattern of pathological changes in the
brain that result in neurodegeneration and the progressive development of dementia. …

Relationship between education and age‐related cognitive decline: A review of recent research

…, NL Saunders, JJ Summers, JC Vickers - …, 2015 - Wiley Online Library
The association between level of educational attainment and cognitive performance is well
studied. People with higher education perform better across a broad range of cognitive tasks. …

Focal demyelination in Alzheimer's disease and transgenic mouse models

…, GM Halliday, CE Shepherd, JC Vickers… - Acta …, 2010 - Springer
We have investigated alterations in myelin associated with Aβ plaques, a major pathological
hallmark of Alzheimer’s disease (AD), in human tissue and relevant transgenic mice models…

Excitotoxicity in ALS: overstimulation, or overreaction?

…, A Woodhouse, MTK Kirkcaldie, JC Vickers - Experimental neurology, 2016 - Elsevier
Amyotrophic lateral sclerosis (ALS) is an adult onset neurodegenerative disease that results
in motor dysfunction and death, generally from respiratory failure. 90% of ALS cases are …

[HTML][HTML] Redefining the role of metallothionein within the injured brain: extracellular metallothioneins play an important role in the astrocyte-neuron response to injury

…, LD Beazley, MI Chuah, JC Vickers… - Journal of biological …, 2008 - ASBMB
A number of intracellular proteins that are protective after brain injury are classically thought
to exert their effect within the expressing cell. The astrocytic metallothioneins (MT) are one …

Altered synapses and gliotransmission in Alzheimer's disease and AD model mice

S Mitew, MTK Kirkcaldie, TC Dickson, JC Vickers - Neurobiology of aging, 2013 - Elsevier
Amyloid-β (Aβ) plaque accumulation in Alzheimer's disease (AD) is associated with
glutamatergic synapse loss, but less is known about its effect on inhibitory synapses. Here, we …

[HTML][HTML] Diffuse axonal injury in brain trauma: insights from alterations in neurofilaments

…, MI Chuah, MTK Kirkcaldie, JC Vickers… - Frontiers in cellular …, 2014 - frontiersin.org
Traumatic brain injury (TBI) from penetrating or closed forces to the cranium can result in a
range of forms of neural damage, which culminate in mortality or impart mild to significant …

Neurochemical diversity of dystrophic neurites in the early and late stages of Alzheimer's disease

…, CE King, GH McCormack, JC Vickers - Experimental neurology, 1999 - Elsevier
We examined the neurochemical and morphological diversity of abnormal neurites associated
with β-amyloid plaque formation in the early and late stages of Alzheimer's disease. …

[HTML][HTML] Delayed plastic responses to anodal tDCS in older adults

…, SJ Kim, GH McCormack, JC Vickers… - Frontiers in aging …, 2014 - frontiersin.org
Despite the abundance of research reporting the neurophysiological and behavioral effects
of transcranial direct current stimulation (tDCS) in healthy young adults and clinical …

Initial calcium release from intracellular stores followed by calcium dysregulation is linked to secondary axotomy following transient axonal stretch injury

…, R Gasperini, Y Liu, L Foa, JC Vickers - Journal of …, 2010 - Wiley Online Library
C, washed with fresh artificial CSF and incubated at 37C for a further 15–20 min prior to
imaging. Images were captured every second using a cooled CCD camera (ORCA, Hamamtsu, …