Crohn’s disease and ulcerative colitis, the two common forms of inflammatory bowel disease
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …

Ulcerative colitis and Crohn's disease are the two main forms of inflammatory bowel disease
(IBD). Here we report the first trans-ancestry association study of IBD, with genome-wide or …

Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-…

Background Crohn's disease and ulcerative colitis are the two major forms of inflammatory
bowel disease; treatment strategies have historically been determined by this binary …

The American College of Cardiology (ACC) develops a number of clinical policy documents
to provide members with guidance on clinical topics. Although clinical practice guidelines …

The interactions between proteins and solvent components have been investigated for the
sucrose/water system. Thermodynamic and kinetic measurements of the thermal unfolding of …

Genetic association studies have identified 215 risk loci for inflammatory bowel disease 1 ,
2 , 3 , 4 , 5 , 6 , 7 , 8 , thereby uncovering fundamental aspects of its molecular biology. We …

Adoptive cell therapy with tumor-targeted T cells is a promising approach to cancer therapy.
Enhanced clinical outcome using this approach requires conditioning regimens with total …

The clinical course of autoimmune and infectious disease varies greatly, even between
individuals with the same condition. An understanding of the molecular basis for this …

Rationale: Primary graft dysfunction (PGD) is the main cause of early morbidity and mortality
after lung transplantation. Previous studies have yielded conflicting results for PGD risk …