Pathogenesis and Diagnosis of Shiga Toxin-Producing Escherichia coli Infections
Since their initial recognition 20 years ago, Shiga toxin-producing Escherichia coli (STEC)
strains have emerged as an important cause of serious human gastrointestinal disease, which …
strains have emerged as an important cause of serious human gastrointestinal disease, which …
Detection and characterization of Shiga toxigenic Escherichia coli by using multiplex PCR assays for stx 1, stx 2, eaeA, enterohemorrhagic E. coli hlyA, rfb O111, and …
Shiga toxigenic Escherichia coli (STEC) comprises a diverse group of organisms capable of
causing severe gastrointestinal disease in humans. Within the STEC family, certain strains …
causing severe gastrointestinal disease in humans. Within the STEC family, certain strains …
The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease
Streptococcus pneumoniae is a Gram-positive bacterial pathogen that colonizes the mucosal
surfaces of the host nasopharynx and upper airway. Through a combination of virulence-…
surfaces of the host nasopharynx and upper airway. Through a combination of virulence-…
Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection
…, E Kurt-Jones, JC Paton… - Proceedings of the …, 2003 - National Acad Sciences
Streptococcus pneumoniae is one of the leading causes of invasive bacterial disease
worldwide. Fragments of the cell wall and the cytolytic toxin pneumolysin have been shown to …
worldwide. Fragments of the cell wall and the cytolytic toxin pneumolysin have been shown to …
Streptococcus pneumoniae: transmission, colonization and invasion
Streptococcus pneumoniae has a complex relationship with its obligate human host. On the
one hand, the pneumococci are highly adapted commensals, and their main reservoir on the …
one hand, the pneumococci are highly adapted commensals, and their main reservoir on the …
Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis
Protein folding by the endoplasmic reticulum (ER) is physiologically critical; its disruption
causes ER stress and augments disease. ER stress activates the unfolded protein response (…
causes ER stress and augments disease. ER stress activates the unfolded protein response (…
AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP
AB 5 toxins are produced by pathogenic bacteria and consist of enzymatic A subunits that
corrupt essential eukaryotic cell functions, and pentameric B subunits that mediate uptake into …
corrupt essential eukaryotic cell functions, and pentameric B subunits that mediate uptake into …
Direct Detection and Characterization of Shiga Toxigenic Escherichia coli by Multiplex PCR for stx1, stx2, eae, ehxA, and saa
We recently described a novel megaplasmid-encoded adhesin produced by certain Shiga
toxigenic Escherichia coli (STEC) strains that lack the locus for enterocyte effacement (LEE) …
toxigenic Escherichia coli (STEC) strains that lack the locus for enterocyte effacement (LEE) …
Characterization of Saa, a Novel Autoagglutinating Adhesin Produced by Locus of Enterocyte Effacement-Negative Shiga-ToxigenicEscherichia coli Strains That Are …
AW Paton, P Srimanote, MC Woodrow… - Infection and …, 2001 - Am Soc Microbiol
The capacity of Shiga toxigenic Escherichia coli(STEC) to adhere to the intestinal mucosa
undoubtedly contributes to pathogenesis of human disease. The majority of STEC strains …
undoubtedly contributes to pathogenesis of human disease. The majority of STEC strains …
[HTML][HTML] A molecular mechanism for bacterial susceptibility to zinc
Transition row metal ions are both essential and toxic to microorganisms. Zinc in excess has
significant toxicity to bacteria, and host release of Zn(II) at mucosal surfaces is an important …
significant toxicity to bacteria, and host release of Zn(II) at mucosal surfaces is an important …