COVID-19, caused by SARS-CoV-2, lacks effective therapeutics. Additionally, no antiviral
drugs or vaccines were developed against the closely related coronavirus, SARS-CoV-1 or …

The regulation of cell shape, fibronectin mRNA level, secretion and assembly by substratum
surface topography was investigated in early passage human gingival fibroblasts cultured …

Fusobacterium nucleatum is closely associated with human periodontal diseases and may
also be a causative agent in other infections, such as pericarditis, septic arthritis, and …

Increased proliferation of mucosal epithelium during inflammation is associated with degradation
of subepithelial connective tissue matrix and local invasion of the epithelial cells. Here …

The mechanism of tetracycline-induced inhibition of matrix metalloproteinases (MMP) was
studied by measuring the MMP secretion and MMP-2 mRNA levels in unkeratinizing …

Since their discovery 1 in 1858, aryl diazonium salts have played a major role in organic
synthesis. They have been widely employed as precursors to diazo dyes 2 and synthetic …

A general and enantioselective synthesis of 2-substituted 2-phenylpyrrolidines and -piperidines,
an important class of pharmaceutically relevant compounds that contain a quaternary …

A new method for the synthesis of enantiopure α-substituted piperazines via direct
functionalization of the intact piperazine ring is described. The approach utilizes the asymmetric …

Fragment‐based drug discovery is now widely adopted for lead generation in the pharmaceutical
industry. However, fragment screening collections are often predominantly populated …

The human ovarian surface epithelium (OSE), or ovarian mesothelium, is functionally complex
as seen by its capacity to proliferate, migrate, and contribute to ovulation and ovulatory …