User profiles for James Howe

James Howe

Department of Materials Science & Engineering, University of Virginia
Verified email at virginia.edu
Cited by 9233

[BOOK][B] Transmission electron microscopy and diffractometry of materials

B Fultz, JM Howe - 2012 - books.google.com
This book explains concepts of transmission electron microscopy (TEM) and x-ray diffractometry
(XRD) that are important for the characterization of materials. The fourth edition adds …

Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC

…, K Toshima, TC Lairmore, JR Howe… - Human molecular …, 1993 - academic.oup.com
Multiple endocrine neoplasia type 2A (MEN 2A) and familial medullary thyroid carcinoma (FMTC)
are dominantly inherited conditions which predispose to the development of endocrine …

Mutations in the SMAD4/DPC4 Gene in Juvenile Polyposis

JR Howe, S Roth, JC Ringold, RW Summers… - Science, 1998 - science.org
Familial juvenile polyposis is an autosomal dominant disease characterized by a predisposition
to hamartomatous polyps and gastrointestinal cancer. Here it is shown that a subset of …

[PDF][PDF] FOXG1-dependent dysregulation of GABA/glutamate neuron differentiation in autism spectrum disorders

…, EL Grigorenko, K Chawarska, KA Pelphrey, JR Howe… - Cell, 2015 - cell.com
Autism spectrum disorder (ASD) is a disorder of brain development. Most cases lack a clear
etiology or genetic basis, and the difficulty of re-enacting human brain development has …

[PDF][PDF] Nomenclature of voltage-gated sodium channels

…, RL Barchi, JH Caldwell, F Hofmann, JR Howe… - Neuron, 2000 - cell.com
Sodium Channels synonyms for many of sodium channel isoforms. To eliminate confusion
resulting from the multiplicity of names, we propose a standardized nomenclature for Voltage-…

Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis

JR Howe, JL Bair, MG Sayed, ME Anderson… - Nature …, 2001 - nature.com
Juvenile polyposis (JP; OMIM 174900) is an autosomal dominant gastrointestinal
hamartomatous polyposis syndrome in which patients are at risk for developing gastrointestinal …

Stargazin modulates AMPA receptor gating and trafficking by distinct domains

…, H Adesnik, M Sekiguchi, W Zhang, K Wada, JR Howe… - Nature, 2005 - nature.com
AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) receptors mediate fast
excitatory synaptic transmission in the brain. These ion channels rapidly deactivate and …

Adenocarcinoma of the small bowel: review of the National Cancer Data Base, 1985–1995

JR Howe, LH Karnell, HR Menck… - … Journal of the …, 1999 - Wiley Online Library
BACKGROUND Small bowel adenocarcinoma (SBA) accounts for 2% of gastrointestinal (GI)
tumors and 1% of GI cancer deaths. The objective of this study was to review the National …

Slow closed-state inactivation: a novel mechanism underlying ramp currents in cells expressing the hNE/PN1 sodium channel

TR Cummins, JR Howe, SG Waxman - Journal of Neuroscience, 1998 - Soc Neuroscience
To better understand why sensory neurons express voltage-gated Na + channel isoforms
that are different from those expressed in other types of excitable cells, we compared the …

Factors predictive of survival in ampullary carcinoma

JR Howe, DS Klimstra, RD Moccia, KC Conlon… - Annals of …, 1998 - journals.lww.com
Objective To review the recent Memorial Sloan-Kettering Cancer Center experience with
adenocarcinoma of the ampulla of Vater and to identify clinicopathologic factors that have an …