THE cyclin-dependent kinase inhibitor p16 is a candidate tumour-suppressor protein that maps
to a genomic locus strongly associated with familial melanoma and other tumour types 1–…

Myopia is a globally emerging concern accompanied by multiple medical and socio-economic
burdens with no well-established causal treatment to control thus far. The study of the …

Antimicrobial resistance (AMR) threatens human, animal, and environmental health.
Acknowledging the urgency of addressing AMR, an opportunity exists to extend AMR action-…

p16 is a key regulator of cellular senescence, yet the drivers of this stable state of proliferative
arrest are not well understood. Here, we identify 22 senescence-associated microRNAs (…

… James Koh, and Nicholas Dyson* repression of E2F-regulated genes (Koh et al., 1995;
Laboratory of Molecular Oncology … As an amined the ability of p16INK4a to arrest cells in G1 (Koh …

The cyclin‐dependent kinase (Cdk) inhibitor p16 Ink4a (p16) is a canonical mediator of cellular
senescence and accumulates in aging tissues, where it constrains proliferation of some …

The molecular mechanisms responsible for aberrant calcium signaling in parathyroid disease
are poorly understood. The loss of appropriate calcium-responsive modulation of PTH …

Abnormal feedback of serum calcium to parathyroid hormone (PTH) secretion is the
hallmark of primary hyperparathyroidism (PHPT). Although the molecular pathogenesis of …

A sample of Korean elders aged 60 and over residing in the New York City area were
interviewed with regard to their living arrangements, service needs, and orientation to filial and …

In this review article, we seek to provide a link between our understanding of the spermatozoa
on the physical aspects and applications involving assisted reproduction, so that future …