Therapeutic options for the treatment of an increasing variety of cancers have been expanded
by the introduction of a new class of drugs, commonly referred to as checkpoint blocking …

Corticotroph-derived glycoprotein hormone (CGH), also referred to as thyrostimulin, is a
noncovalent heterodimer of glycoprotein hormone α 2 (GPHA2) and glycoprotein hormone β 5 (…

Epithelial-to-mesenchymal transition (EMT) is associated with tumor initiation, metastasis,
and drug resistance. However, the mechanisms underlying these associations are largely …

A marker based on randomly amplified polymorphic DNA (RAPD), OT-38, was discovered
that nonlethally discriminates between stream-type and ocean-type populations of chinook …

A randomized clinical trial assessed the effectiveness of control, low-intensity, and high-intensity
stop-smoking treatments in a Department of Veterans Affairs outpatient setting. The …

Ordering genes on a chromosome is similar to the traveling salesman problem (TSP), but
with some extra information. This extra information prompted us to investigate the genetic …

We investigate the running time of several algorithms to compute the nth element of the
Fibonacci sequence. Since the nth Fibonacci number grows exponentially with n, the number of …

The cystatin superfamily of cysteine proteinase inhibitors consists of three major families. In
the present study, we report the cloning of the cDNA for mouse cystatin T, which is related to …

Background Resistance to immune checkpoint inhibitors and targeted treatments for cancer
is common; thus, novel immunotherapy agents are needed. Urelumab is a monoclonal …

The decision about what operators to allow and how to charge for these operations when
aligning strings that arise in a biological context is the decision about what model of evolution …