User profiles for James Lennon

James Lennon

Student, Harvard University
Verified email at college.harvard.edu
Cited by 104

Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma

HS Venkatesh, LT Tam, PJ Woo, J Lennon, S Nagaraja… - Nature, 2017 - nature.com
High-grade gliomas (HGG) are a devastating group of cancers, and represent the leading
cause of brain tumour-related death in both children and adults. Therapies aimed at …

NF1 mutation drives neuronal activity-dependent initiation of optic glioma

…, Y Ma, KC Chang, X Xia, JA Toonen, JJ Lennon… - Nature, 2021 - nature.com
Neurons have recently emerged as essential cellular constituents of the tumour microenvironment,
and their activity has been shown to increase the growth of a diverse number of solid …

[PDF][PDF] Neural precursor-derived pleiotrophin mediates subventricular zone invasion by glioma

EY Qin, DD Cooper, KL Abbott, J Lennon, S Nagaraja… - Cell, 2017 - cell.com
The lateral ventricle subventricular zone (SVZ) is a frequent and consequential site of pediatric
and adult glioma spread, but the cellular and molecular mechanisms mediating this are …

[HTML][HTML] Diabetes impairs the angiogenic potential of adipose-derived stem cells by selectively depleting cellular subpopulations

…, D Duscher, R Kosaraju, MT Chung, J Lennon… - Stem cell research & …, 2014 - Springer
Introduction Pathophysiologic changes associated with diabetes impair new blood vessel
formation and wound healing. Mesenchymal stem cells derived from adipose tissue (ASCs) …

Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening

…, S Kreimer, EY Qin, X Zhang, J Lennon… - Science translational …, 2019 - science.org
Diffuse midline gliomas (DMGs) are universally lethal malignancies occurring chiefly during
childhood and involving midline structures of the central nervous system, including thalamus…

[PDF][PDF] Histone variant and cell context determine H3K27M reprogramming of the enhancer landscape and oncogenic state

…, MA Quezada, SM Gillespie, M Arzt, JJ Lennon… - Molecular cell, 2019 - cell.com
Development of effective targeted cancer therapies is fundamentally limited by our molecular
understanding of disease pathogenesis. Diffuse intrinsic pontine glioma (DIPG) is a fatal …

Capillary force seeding of hydrogels for adipose-derived stem cell delivery in wounds

…, R Kosaraju, LJ Auerbach, J Lennon… - Stem cells …, 2014 - academic.oup.com
James Lennon , James Lennon … Auerbach, James Lennon, Michael T. Chung, Kevin
Paik, Johannes Nimpf, Jayakumar Rajadas, Michael T. Longaker, Geoffrey C. …

[PDF][PDF] Design Continuums and the Path Toward Self-Designing Key-Value Stores that Know and Learn.

…, W Qin, M Akmanalp, S Hilgard, A Ross, J Lennon… - CIDR, 2019 - nivdayan.github.io
We introduce the concept of design continuums for the data layout of key-value stores. A
design continuum unifies major distinct data structure designs under the same model. The …

[HTML][HTML] Assessing the Role of MicroRNAs in Predicting Breast Cancer Recurrence—A Systematic Review

L Bouz Mkabaah, MG Davey, JC Lennon… - International Journal of …, 2023 - mdpi.com
Identifying patients likely to develop breast cancer recurrence remains a challenge. Thus,
the discovery of biomarkers capable of diagnosing recurrence is of the utmost importance. …

Early intervention in reading: Results of a screening and intervention program for kindergarten students

JE Lennon, C Slesinski - School Psychology Review, 1999 - Taylor & Francis
Kindergarten students were selected for participation in a reading intervention program on
the basis of their ability to name the letters of the alphabet. The intervention consisted of 1:2 …