An improved assembly and annotation of the allohexaploid wheat genome identifies complete families of agronomic genes and provides genomic evidence for …

…, D Heavens, H Chapman, J Lipscombe… - Genome …, 2017 - genome.cshlp.org
Advances in genome sequencing and assembly technologies are generating many high-quality
genome sequences, but assemblies of large, repeat-rich polyploid genomes, such as …

Defining cell identity with single‐cell omics

L Mincarelli, A Lister, J Lipscombe, IC Macaulay - Proteomics, 2018 - Wiley Online Library
Cells are a fundamental unit of life, and the ability to study the phenotypes and behaviors of
individual cells is crucial to understanding the workings of complex biological systems. Cell …

[HTML][HTML] An accessible, efficient and global approach for the large-scale sequencing of bacterial genomes

…, GF Dykes, C Schudoma, W Rowe, J Lipscombe… - Genome biology, 2021 - Springer
We have developed an efficient and inexpensive pipeline for streamlining large-scale
collection and genome sequencing of bacterial isolates. Evaluation of this method involved a …

Norwich COVID-19 testing initiative pilot: evaluating the feasibility of asymptomatic testing on a university campus

…, M Hitchcock, N Irish, J Lipscombe… - Journal of Public …, 2021 - academic.oup.com
Background There is a high prevalence of COVID-19 in university-age students, who are
returning to campuses. There is little evidence regarding the feasibility of universal, …

[HTML][HTML] Identification of a non-canonical ciliate nuclear genetic code where UAA and UAG code for different amino acids

J McGowan, ES Kilias, E Alacid, J Lipscombe… - Plos …, 2023 - journals.plos.org
The genetic code is one of the most highly conserved features across life. Only a few lineages
have deviated from the “universal” genetic code. Amongst the few variants of the genetic …

[HTML][HTML] Computational prediction and experimental validation of Salmonella Typhimurium SopE-mediated fine-tuning of autophagy in intestinal epithelial cells

…, AC Jacomin, L Gul, A Lister, J Lipscombe… - Frontiers in Cellular …, 2022 - frontiersin.org
Macroautophagy is a ubiquitous homeostasis and health-promoting recycling process of
eukaryotic cells, targeting misfolded proteins, organelles and intracellular infectious agents. …

[HTML][HTML] Chromosome-level genome sequence of the Genetically Improved Farmed Tilapia (GIFT, Oreochromis niloticus) highlights regions of introgression with O …

…, F Fraser, N Irish, GG Kaithakottil, J Lipscombe… - BMC genomics, 2022 - Springer
Background The Nile tilapia (Oreochromis niloticus) is the third most important freshwater
fish for aquaculture. Its success is directly linked to continuous breeding efforts focusing on …

Genomic and phylogenetic analysis of Salmonella Typhimurium and its monophasic variants responsible for invasive endemic infections in Colombia

…, D Heavens, R Low, C Schudoma, J Lipscombe… - BioRxiv, 2019 - biorxiv.org
Salmonellosis is an endemic human infection, associated with both sporadic cases and
outbreaks throughout Colombia. Typhimurium is the most common Colombian serovar of …

[HTML][HTML] High-throughput retrotransposon-based fluorescent markers: improved information content and allele discrimination

M Knox, C Moreau, J Lipscombe, D Baker, N Ellis - Plant Methods, 2009 - Springer
Background Dense genetic maps, together with the efficiency and accuracy of their construction,
are integral to genetic studies and marker assisted selection for plant breeding. High-…

Single-cell and spatial transcriptomics of the avian embryo tailbud

…, S Turner, EL Smith, L Mincarelli, A Lister, J Lipscombe… - bioRxiv, 2024 - biorxiv.org
Vertebrate body axis formation initiates during gastrulation and continues within the tail bud
at the posterior end of the embryo. Major structures in the trunk are paired somites, which …