Side effects of antidepressants can be predicted by receptor selectivity and site of action.
Although the selective serotonin reuptake inhibitors (SSRIs) have better overall safety and …

… Blackburn, f James M. … 2 70 m ._ … Fantino M, Souquet AM. Effects of metabolites 1
and 2 of sibutramine on the short-term control of food intake in the rat. Int J Obes. …

Viral whole-genome sequencing (WGS) provides critical insight into the transmission and
evolution of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Long-read …

In a placebo-controlled, double-blind study of the unique antidepressant agent bupropion in
the treatment of nondepressed subjects with bulimia (bupropion group, N= 55; placebo …

High-throughput single-cell RNA sequencing is a powerful technique but only generates
short reads from one end of a cDNA template, limiting the reconstruction of highly diverse …

More than 50 neurological and neuromuscular diseases are caused by short tandem repeat
(STR) expansions, with 37 different genes implicated to date. We describe the use of …

Nanopore sequencing depends on the FAST5 file format, which does not allow efficient
parallel analysis. Here we introduce SLOW5, an alternative format engineered for efficient …

Impaired cognitive functioning is often associated with major depressive disorder (MDD).
Moreover, a number of agents used to treat MDD are known to have negative effects on …

Objective: To assess the efficacy and safety of flexible-dose memantine in patients with major
depressive disorder (MDD). Methods: In this 12-week, single-center, open-label study, 8 …

Sexual dysfunction has long been noted as both a symptom of depressive illness and as a
side effect of many of the medications used to treat depression. Although most people …