New colorimetric cytotoxicity assay for anticancer-drug screening
…, D Scudiero, A Monks, J McMahon… - JNCI: Journal of the …, 1990 - academic.oup.com
We have developed a rapid, sensitive, and inexpensive method for measuring the cellular
protein content of adherent and suspension cultures in 96-well microtiter plates. The method …
protein content of adherent and suspension cultures in 96-well microtiter plates. The method …
Possible artifacts of data biases in the recent global surface warming hiatus
…, A Arguez, B Huang, JH Lawrimore, JR McMahon… - Science, 2015 - science.org
Much study has been devoted to the possible causes of an apparent decrease in the upward
trend of global surface temperatures since 1998, a phenomenon that has been dubbed the …
trend of global surface temperatures since 1998, a phenomenon that has been dubbed the …
Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to …
MR Boyd, KR Gustafson, JB McMahon… - Antimicrobial agents …, 1997 - Am Soc Microbiol
We have isolated and sequenced a novel 11-kDa virucidal protein, named cyanovirin-N (CV-N),
from cultures of the cyanobacterium (blue-green alga) Nostoc ellipsosporum. We also …
from cultures of the cyanobacterium (blue-green alga) Nostoc ellipsosporum. We also …
[BOOK][B] Human settlements, infrastructure, and spatial planning
The shift from rural to more urban societies is a global trend with significant consequences
for greenhouse gas (GHG) emissions and climate change mitigation. Across multiple …
for greenhouse gas (GHG) emissions and climate change mitigation. Across multiple …
[HTML][HTML] Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy
<p>Human immunodeficiency virus (HIV) persistence in latently infected resting memory
CD4+ T-cells is the major barrier to HIV cure. Cellular histone deacetylases (HDACs) are …
CD4+ T-cells is the major barrier to HIV cure. Cellular histone deacetylases (HDACs) are …
[HTML][HTML] Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp.
…, JA Turpin, RW Buckheit, JB McMahon… - Journal of Biological …, 2005 - ASBMB
Griffithsin (GRFT), a novel anti-HIV protein, was isolated from an aqueous extract of the red
alga Griffithsia sp. The 121-amino acid sequence of GRFT has been determined, and …
alga Griffithsia sp. The 121-amino acid sequence of GRFT has been determined, and …
Rapid generation of durable B cell memory to SARS-CoV-2 spike and nucleocapsid proteins in COVID-19 and convalescence
…, PM Aui, N Varese, S Stojanovic, J McMahon… - Science …, 2020 - science.org
Lasting immunity following SARS-CoV-2 infection is questioned because serum antibodies
decline in convalescence. However, functional immunity is mediated by long-lived memory T …
decline in convalescence. However, functional immunity is mediated by long-lived memory T …
[HTML][HTML] Monkeypox infection presenting as genital rash, Australia, May 2022
Rapid diagnosis and whole genome sequencing confirmed a case of monkeypox in an HIV-positive
individual receiving antiretroviral therapy. The patient had a normal CD4+ T-cell …
individual receiving antiretroviral therapy. The patient had a normal CD4+ T-cell …
Hydroxyapatite-coated femoral stems. Histological analysis of components retrieved at autopsy.
TW Bauer, RC Geesink, R Zimmerman, JT McMahon - JBJS, 1991 - journals.lww.com
Plasma-sprayed coating of hydroxyapatite are biocompatible and, because of their
osteoconductive properties, may contribute to the early fixation of total joint prostheses. To evaluate …
osteoconductive properties, may contribute to the early fixation of total joint prostheses. To evaluate …
Identification of a broadly fibrogenic macrophage subset induced by type 3 inflammation
Macrophages are central orchestrators of the tissue response to injury, with distinct macrophage
activation states playing key roles in fibrosis progression and resolution. Identifying key …
activation states playing key roles in fibrosis progression and resolution. Identifying key …