Why prokaryotes have pangenomes
JO McInerney, A McNally, MJ O'connell - Nature microbiology, 2017 - nature.com
The existence of large amounts of within-species genome content variability is puzzling.
Population genetics tells us that fitness effects of new variants—either deleterious, neutral or …
Population genetics tells us that fitness effects of new variants—either deleterious, neutral or …
Endosymbiotic origin and differential loss of eukaryotic genes
Chloroplasts arose from cyanobacteria, mitochondria arose from proteobacteria. Both
organelles have conserved their prokaryotic biochemistry, but their genomes are reduced, and …
organelles have conserved their prokaryotic biochemistry, but their genomes are reduced, and …
Origins of major archaeal clades correspond to gene acquisitions from bacteria
The mechanisms that underlie the origin of major prokaryotic groups are poorly understood.
In principle, the origin of both species and higher taxa among prokaryotes should entail …
In principle, the origin of both species and higher taxa among prokaryotes should entail …
Networks: expanding evolutionary thinking
Networks allow the investigation of evolutionary relationships that do not fit a tree model.
They are becoming a leading tool for describing the evolutionary relationships between …
They are becoming a leading tool for describing the evolutionary relationships between …
The hybrid nature of the Eukaryota and a consilient view of life on Earth
JO McInerney, MJ O'connell, D Pisani - Nature Reviews Microbiology, 2014 - nature.com
The origin of the eukaryotic cell, which is known as eukaryogenesis, has puzzled scientists
for more than 100 years, and many hypotheses have been proposed. Recent analyses of …
for more than 100 years, and many hypotheses have been proposed. Recent analyses of …
Heterogeneous models place the root of the placental mammal phylogeny
…, D Pisani, JO McInerney, MJ O'Connell - Molecular biology …, 2013 - academic.oup.com
Heterogeneity among life traits in mammals has resulted in considerable phylogenetic conflict,
particularly concerning the position of the placental root. Layered upon this are gene- and …
particularly concerning the position of the placental root. Layered upon this are gene- and …
Of clades and clans: terms for phylogenetic relationships in unrooted trees
During the late 1980s, the molecular biology community became aware that the words ‘homology’and
‘similarity’were being used in much of the scientific literature as though they were …
‘similarity’were being used in much of the scientific literature as though they were …
Does a tree–like phylogeny only exist at the tips in the prokaryotes?
…, M Wilkinson, JO McInerney - … of the Royal …, 2004 - royalsocietypublishing.org
The extent to which prokaryotic evolution has been influenced by horizontal gene transfer (HGT)
and therefore might be more of a network than a tree is unclear. Here we use supertree …
and therefore might be more of a network than a tree is unclear. Here we use supertree …
[HTML][HTML] Population genomics reveal recent speciation and rapid evolutionary adaptation in polar bears
…, CC Morgan, A Doherty, MJ O'Connell, JO McInerney… - Cell, 2014 - cell.com
Polar bears are uniquely adapted to life in the High Arctic and have undergone drastic
physiological changes in response to Arctic climates and a hyperlipid diet of primarily marine …
physiological changes in response to Arctic climates and a hyperlipid diet of primarily marine …
GCUA: general codon usage analysis.
JO McInerney - Bioinformatics (Oxford, England), 1998 - academic.oup.com
The program General Codon Usage Analysis (GCUA) has been developed for analysing
codon and amino acid usage patterns. AVAILABILITY: ftp://ftp.nhm.ac.uk/pub/gcua. Freely …
codon and amino acid usage patterns. AVAILABILITY: ftp://ftp.nhm.ac.uk/pub/gcua. Freely …