User profiles for James P. Lingford

James Lingford

Monash University
Verified email at monash.edu
Cited by 511

[HTML][HTML] An artificial PPR scaffold for programmable RNA recognition

…, A Filipovska, T Chia, L Rajappa, JP Lingford… - Nature …, 2014 - nature.com
Pentatricopeptide repeat (PPR) proteins control diverse aspects of RNA metabolism in
eukaryotic cells. Although recent computational and structural studies have provided insights into …

Synthesis of C-mannosylated glycopeptides enabled by Ni-catalyzed photoreductive cross-coupling reactions

…, S Shah, MJ Roy, A John, JP Lingford… - Journal of the …, 2021 - ACS Publications
The biological functions of tryptophan C-mannosylation are poorly understood, in part, due
to a dearth of methods for preparing pure glycopeptides and glycoproteins with this …

[HTML][HTML] Protein O-fucosylation in Plasmodium falciparum ensures efficient infection of mosquito and vertebrate hosts

…, ASP Yang, A John, NE Scott, JP Lingford… - Nature …, 2017 - nature.com
O-glycosylation of the Plasmodium sporozoite surface proteins CSP and TRAP was recently
identified, but the role of this modification in the parasite life cycle and its relevance to …

Oxidative desulfurization pathway for complete catabolism of sulfoquinovose by bacteria

M Sharma, JP Lingford, M Petricevic… - Proceedings of the …, 2022 - National Acad Sciences
Catabolism of sulfoquinovose (SQ; 6-deoxy-6-sulfoglucose), the ubiquitous sulfosugar produced
by photosynthetic organisms, is an important component of the biogeochemical carbon …

[HTML][HTML] Trefoil factors share a lectin activity that defines their role in mucus

MA Järvå, JP Lingford, A John, NM Soler… - Nature …, 2020 - nature.com
The mucosal epithelium secretes a host of protective disulfide-rich peptides, including the
trefoil factors (TFFs). The TFFs increase the viscoelasticity of the mucosa and promote cell …

Structural and biochemical insights into the function and evolution of sulfoquinovosidases

P Abayakoon, Y Jin, JP Lingford, M Petricevic… - ACS central …, 2018 - ACS Publications
An estimated 10 billion tonnes of sulfoquinovose (SQ) are produced and degraded each
year. Prokaryotic sulfoglycolytic pathways catabolize sulfoquinovose (SQ) liberated from plant …

Molecular basis of sulfosugar selectivity in sulfoglycolysis

…, P Abayakoon, R Epa, Y Jin, JP Lingford… - ACS Central …, 2021 - ACS Publications
The sulfosugar sulfoquinovose (SQ) is produced by essentially all photosynthetic organisms
on Earth and is metabolized by bacteria through the process of sulfoglycolysis. The …

[HTML][HTML] Trace gas oxidation sustains energy needs of a thermophilic archaeon at suboptimal temperatures

…, R Grinter, E Tudor-Matthew, JP Lingford… - Nature …, 2024 - nature.com
Diverse aerobic bacteria use atmospheric hydrogen (H 2 ) and carbon monoxide (CO) as
energy sources to support growth and survival. Such trace gas oxidation is recognised as a …

[HTML][HTML] Structural basis of substrate recognition and catalysis by fucosyltransferase 8

MA Järvå, M Dramicanin, JP Lingford, R Mao… - Journal of Biological …, 2020 - ASBMB
Fucosylation of the innermost GlcNAc of N-glycans by fucosyltransferase 8 (FUT8) is an
important step in the maturation of complex and hybrid N-glycans. This simple modification can …

Comprehensive synthesis of substrates, intermediates, and products of the sulfoglycolytic Embden–Meyerhoff–Parnas pathway

…, PL van der Peet, Y Zhang, JP Lingford… - The Journal of …, 2019 - ACS Publications
Sulfoglycolysis is a metabolic pathway dedicated to the catabolism of the sulfosugar
sulfoquinovose (SQ) into smaller organosulfur fragments. An estimated 10 billion tonnes of SQ …