User profiles for James P. Roach
James RoachPostdoctoral Scholar; University of California Los Angeles Verified email at ucla.edu Cited by 318 |
[HTML][HTML] Choice selective inhibition drives stability and competition in decision circuits
During perceptual decision-making, the firing rates of cortical neurons reflect upcoming
choices. Recent work showed that excitatory and inhibitory neurons are equally selective for …
choices. Recent work showed that excitatory and inhibitory neurons are equally selective for …
[HTML][HTML] Connexin 43 gap junctions contribute to brain endothelial barrier hyperpermeability in familial cerebral cavernous malformations type III by modulating tight …
AM Johnson, JP Roach, A Hu, SM Stamatovic… - The FASEB …, 2018 - ncbi.nlm.nih.gov
Familial cerebral cavernous malformations type III (fCCM3) is a disease of the cerebrovascular
system caused by loss-of-function mutations in ccm3 that result in dilated capillary beds …
system caused by loss-of-function mutations in ccm3 that result in dilated capillary beds …
Resonance with subthreshold oscillatory drive organizes activity and optimizes learning in neural networks
Network oscillations across and within brain areas are critical for learning and performance
of memory tasks. While a large amount of work has focused on the generation of neural …
of memory tasks. While a large amount of work has focused on the generation of neural …
[HTML][HTML] Acetylcholine mediates dynamic switching between information coding schemes in neuronal networks
Rate coding and phase coding are the two major coding modes seen in the brain. For these
two modes, network dynamics must either have a wide distribution of frequencies for rate …
two modes, network dynamics must either have a wide distribution of frequencies for rate …
Memory recall and spike-frequency adaptation
JP Roach, LM Sander, MR Zochowski - Physical Review E, 2016 - APS
The brain can reproduce memories from partial data; this ability is critical for memory recall.
The process of memory recall has been studied using autoassociative networks such as the …
The process of memory recall has been studied using autoassociative networks such as the …
[HTML][HTML] Formation and dynamics of waves in a cortical model of cholinergic modulation
JP Roach, E Ben-Jacob, LM Sander… - PLoS computational …, 2015 - journals.plos.org
Acetylcholine (ACh) is a regulator of neural excitability and one of the neurochemical substrates
of sleep. Amongst the cellular effects induced by cholinergic modulation are a reduction …
of sleep. Amongst the cellular effects induced by cholinergic modulation are a reduction …
[HTML][HTML] 25th annual computational neuroscience meeting: CNS-2016
…, C Metzner, A Schweikard, B Zurowski, JP Roach… - BMC neuroscience, 2016 - Springer
Neural circuits are notorious for the complexity of their organization. Part of this complexity
is related to the number of different cell types that work together to encode stimuli. I will …
is related to the number of different cell types that work together to encode stimuli. I will …
Social regulation of electric signal plasticity in male Brachyhypopomus gauderio
S Gavassa, JP Roach, PK Stoddard - Journal of Comparative Physiology …, 2013 - Springer
In animal communication, the social context that elicits particular dynamic changes in the
signal can provide indirect clues to signal function. Female presence should increase the …
signal can provide indirect clues to signal function. Female presence should increase the …
A possible mechanism for redox control of human neuroglobin activity
AN Morozov, JP Roach, M Kotzer… - Journal of Chemical …, 2014 - ACS Publications
Neuroglobin (Ngb) promotes neuron survival under hypoxic/ischemic conditions. In vivo and
in vitro assays provide evidence for redox-regulated functioning of Ngb. On the basis of X-…
in vitro assays provide evidence for redox-regulated functioning of Ngb. On the basis of X-…
Two roles for choice selective inhibition in decision-making circuits
During perceptual decision-making, the firing rates of cortical neurons reflect upcoming
choices. Recent work showed that excitatory and inhibitory neurons are equally selective for …
choices. Recent work showed that excitatory and inhibitory neurons are equally selective for …