Microvesicles are generated by the outward budding and fission of membrane vesicles from
the cell surface. Recent studies suggest that microvesicle shedding is a highly regulated …

Recent advances in the study of tumor-derived microvesicles reveal new insights into the
cellular basis of disease progression and the potential to translate this knowledge into …

Tumor cells release extracellular vesicles (EVs) that can function as mediators of intercellular
communication in the tumor microenvironment. EVs contain a host of bioactive cargo, …

Cells release multiple, distinct forms of extracellular vesicles including structures known as
microvesicles, which are known to alter the extracellular environment. Despite growing …

Tumor cell invasion requires the molecular and physical adaptation of both the cell and its
microenvironment. Here we show that tumor cells are able to switch between the use of …

Tumour-derived microvesicles (TMVs) comprise a class of extracellular vesicles released from
tumour cells that are now understood to facilitate communication between the tumour and …

Microvesicles are a heterogeneous group of membrane‐enclosed vesicles that are released
from cells into the extracellular space by the outward budding and pinching of the plasma …

Breast cancer brain metastases (BCBM) have a 5-20 year latency and account for 30% of
mortality; however, mechanisms governing adaptation to the brain microenvironment remain …

Extracellular vesicles and particles have important roles in physiology and disease. Advances
in isolation and characterization technologies have enabled the identification of new …

Tumor cell invasion is one result of the bidirectional interactions occurring between tumor
cells and the surrounding milieu. The ability of tumor cells to invade through the extracellular …