Adjuvant effects of IL-1β, IL-2, IL-8, IL-15, IFN-α, IFN-γ TGF-β4 and lymphotactin on DNA vaccination against Eimeria acervulina

…, J Burnside, KC Weining, P Staeheli, JJ Zhu - Vaccine, 2001 - Elsevier
Eight chicken cytokine genes (IL-1β, IL-2, IL-8, IL-15, IFN-α, IFN-γ, TGF-β4, lymphotactin)
were evaluated for their adjuvant effect on a suboptimal dose of an Eimeria DNA vaccine …

Deep learning-based prediction of the T cell receptor–antigen binding specificity

T Lu, Z Zhang, J Zhu, Y Wang, P Jiang, X Xiao… - Nature machine …, 2021 - nature.com
Neoantigens play a key role in the recognition of tumour cells by T cells; however, only a
small proportion of neoantigens truly elicit T-cell responses, and few clues exist as to which …

[PDF][PDF] SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2

…, R Zang, TT Su, A Herrera, M Zhou, R Yan, J Cui, J Zhu… - Immunity, 2021 - cell.com
Despite mounting evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
engagement with immune cells, most express little, if any, of the canonical receptor of …

Development of a highly effective African swine fever virus vaccine by deletion of the I177L gene results in sterile immunity against the current epidemic Eurasia strain

…, LG Holinka, L Velazquez-Salinas, J Zhu… - Journal of …, 2020 - Am Soc Microbiol
African swine fever virus (ASFV) is the etiological agent of a contagious and often lethal disease
of domestic pigs that has significant economic consequences for the swine industry. The …

Identification and sequence analysis of chicken Toll-like receptors

A Yilmaz, S Shen, DL Adelson, S Xavier, JJ Zhu - Immunogenetics, 2005 - Springer
Toll-like receptors (TLRs) play an important role in the recognition of microbial components.
Only chicken TLR2 and -4 have been reported in the literature. The objectives of this study …

Phase 2 trial of stereotactic ablative radiotherapy for patients with primary renal cancer

…, I Pedrosa, P Kapur, A Garant, C Ahn, A Christie, J Zhu… - European urology, 2023 - Elsevier
Background Most renal cell carcinomas (RCCs) are localized and managed by active
surveillance, surgery, or minimally invasive techniques. Stereotactic ablative radiation (SAbR) may …

[HTML][HTML] Mechanisms of African swine fever virus pathogenesis and immune evasion inferred from gene expression changes in infected swine macrophages

JJ Zhu, P Ramanathan, EA Bishop, V O'Donnell… - PloS one, 2019 - journals.plos.org
African swine fever (ASF) is a swine disease caused by a large, structurally complex, double-stranded
DNA virus, African swine fever virus (ASFV). In domestic pigs, acute infection by …

Ebola vaccine–induced protection in nonhuman primates correlates with antibody specificity and Fc-mediated effects

…, EO Saphire, PL Collins, JE Crowe Jr, JJ Zhu… - Science translational …, 2021 - science.org
Although substantial progress has been made with Ebola virus (EBOV) vaccine measures,
the immune correlates of vaccine-mediated protection remain uncertain. Here, five mucosal …

[HTML][HTML] Antiviral activity of bovine type III interferon against foot-and-mouth disease virus

…, M Weiss, E Perez-Martín, MJ Koster, J Zhu… - Virology, 2011 - Elsevier
Foot-and-mouth disease (FMD) is one of the most serious threats to the livestock industry.
Despite the availability of a vaccine, recent outbreaks in disease-free countries have …

Transcriptome Analysis of Genes Controlled by luxS/Autoinducer-2 in Salmonella enterica Serovar Typhimurium

…, SE Dowd, KA Soni, ME Hume, J Zhu… - Foodborne …, 2010 - liebertpub.com
The enteric pathogen Salmonella enterica serovar Typhimurium uses autoinducer-2 (AI-2) as
a signaling molecule. AI-2 requires the luxS gene for its synthesis. The regulation of global …