Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses a public health threat
for which preventive and therapeutic agents are urgently needed. Neutralizing antibodies …

SARS-CoV-2 poses a public health threat for which therapeutic agents are urgently needed.
Herein, we report that high-throughput microfluidic screening of antigen-specific B-cells led …

The tumorigenic potential of dulaglutide was evaluated in rats and transgenic mice. Rats
were injected sc twice weekly for 93 weeks with dulaglutide 0, 0.05, 0.5, 1.5, or 5 mg/kg …

Glucagon-like peptide-1 (GLP-1) receptor agonists, used for the treatment of type 2 diabetes,
have caused hyperplasia/neoplasia of thyroid C cells in rodent carcinogenicity studies. …

Glucagon-like peptide-1 (GLP-1) receptor agonist therapy has been implicated as a possible
risk factor for acute pancreatitis in patients with type 2 diabetes. Dulaglutide is a long-acting …

Basaglar ® /Abasaglar ® (Lilly insulin glargine [LY IGlar]) is a long-acting human insulin
analogue drug product granted marketing authorisation as a biosimilar to Lantus ® (Sanofi …

Clinical and nonclinical studies have implicated glucagon-like peptide-1 (GLP-1) receptor
agonist therapy as a risk factor for acute pancreatitis in patients with type 2 diabetes. Therefore…

Basal insulin peglispro (BIL) consists of insulin lispro with a 20-kDa polyethylene glycol (PEG)
moiety covalently attached to lysine B28. Because chronic parenteral administration of …

The potential immunotoxicity of tabalumab was assessed as a component of standard pre-clinical
toxicology studies in cynomolgus monkeys. To evaluate potential tabalumab-…

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