The effect of environmental enrichment on behavioral variability depends on genotype, behavior, and type of enrichment

J Akhund-Zade, S Ho, C O'Leary… - Journal of …, 2019 - journals.biologists.com
Non-genetic individuality in behavior, also termed intragenotypic variability, has been
observed across many different organisms. A potential cause of intragenotypic variability is …

Variability in thermal and phototactic preferences in Drosophila may reflect an adaptive bet-hedging strategy

JS Kain, S Zhang, J Akhund-Zade, ADT Samuel… - …, 2015 - academic.oup.com
Organisms use various strategies to cope with fluctuating environmental conditions. In diversified
bet-hedging, a single genotype exhibits phenotypic heterogeneity with the expectation …

[HTML][HTML] Precise quantification of behavioral individuality from 80 million decisions across 183,000 flies

…, C O'Leary, P Reimers, J Akhund-Zade… - Frontiers in Behavioral …, 2022 - frontiersin.org
Individual animals behave differently from each other. This variability is a component of
personality and arises even when genetics and environment are held constant. Discovering the …

Circulating microbial cell–free DNA is increased during neutropenia after hematopoietic stem cell transplantation

LM Blair, J Akhund-Zade, ZA Katsamakis… - Blood …, 2023 - ashpublications.org
We used a next-generation sequencing platform to characterize microbial cell–free DNA (mcfDNA)
in plasma samples from patients undergoing allogeneic hematopoietic stem cell …

Genetic basis of offspring number–body weight tradeoff in Drosophila melanogaster

J Akhund-Zade, S Lall, E Gajda, D Yoon, JF Ayroles… - G3, 2021 - academic.oup.com
Drosophila melanogaster egg production, a proxy for fecundity, is an extensively studied life-history
trait with a strong genetic basis. As eggs develop into larvae and adults, space and …

Analytical and Clinical Validation of Direct Detection of Antimicrobial Resistance Markers by Plasma Microbial Cell-free DNA Sequencing

FC Christians, J Akhund-Zade, KJ Jarman… - medRxiv, 2024 - medrxiv.org
Sequencing of plasma microbial cell-free DNA (mcfDNA) has gained increased acceptance
as a valuable adjunct to standard-of-care testing for diagnosis of infections throughout the …

The genetic basis of natural variation in Drosophila (Diptera: Drosophilidae) virgin egg retention

J Akhund-Zade, AO Bergland, SO Crowe… - Journal of Insect …, 2017 - academic.oup.com
Drosophila melanogaster is able to thrive in harsh northern climates through adaptations in
life-history traits and physiological mechanisms that allow for survival through the winter. We …

Wild flies hedge their thermal preference bets in response to seasonal fluctuations

J Akhund-Zade, D Yoon, A Bangerter, N Polizos… - Biorxiv, 2020 - biorxiv.org
Fluctuating environmental pressures can challenge organisms by repeatedly shifting the
optimum phenotype. Two contrasting evolutionary strategies to cope with these fluctuations are …

The Role of Environment in Drosophila Behavioral Variability and the Genetics of Life History Variation

J Akhund-Zade - 2020 - search.proquest.com
Phenotypic differences among individuals are ubiquitous, but our understanding of their origins
and evolutionary consequences is still not complete. Previous work has identified within-…

Genetic basis of offspring number and body weight variation in Drosophila melanogaster

J Akhund-Zade, S Lall, E Gajda, D Yoon, B de Bivort - bioRxiv, 2020 - biorxiv.org
Drosophila melanogaster egg production, a proxy for fecundity, is an extensively studied life-history
trait with a strong genetic basis. As eggs develop into larvae and adults, space and …