User profiles for Janaina de Freitas Nascimento

Janaína de Freitas Nascimento

Post-doctoral Researcher - Universidade de São Paulo - USP
Verified email at usp.br
Cited by 441

[HTML][HTML] The uptake and metabolism of amino acids, and their unique role in the biology of pathogenic trypanosomatids

L Marchese, JF Nascimento, FS Damasceno… - Pathogens, 2018 - mdpi.com
Trypanosoma brucei, as well as Trypanosoma cruzi and more than 20 species of the genus
Leishmania, form a group of flagellated protists that threaten human health. These …

[PDF][PDF] On-site ribosome remodeling by locally synthesized ribosomal proteins in axons

…, R Cagnetta, A Dwivedy, J de Freitas Nascimento… - Cell reports, 2019 - cell.com
Ribosome assembly occurs mainly in the nucleolus, yet recent studies have revealed robust
enrichment and translation of mRNAs encoding many ribosomal proteins (RPs) in axons, far …

Codon choice directs constitutive mRNA levels in trypanosomes

J de Freitas Nascimento, S Kelly, J Sunter… - Elife, 2018 - elifesciences.org
10.7554/eLife.32467.001 Selective transcription of individual protein coding genes does not
occur in trypanosomes and the cellular copy number of each mRNA must be determined …

Cloning and characterisation of the Equilibrative Nucleoside Transporter family of Trypanosoma cruzi: Ultra-high affinity and selectivity to survive in the intracellular …

GD Campagnaro, J de Freitas Nascimento… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Background Trypanosoma cruzi, the causative agent of Chagas' disease is unable to
synthesise its own purines and relies on salvage from the host. In other protozoa, purine uptake …

Characterization of RBP9 and RBP10, two developmentally regulated RNA-binding proteins in Trypanosoma brucei

…, S Kelly, J de Freitas Nascimento… - Open …, 2017 - royalsocietypublishing.org
The fate of an mRNA is determined by its interaction with proteins and small RNAs within
dynamic complexes called ribonucleoprotein complexes (mRNPs). In Trypanosoma brucei and …

The branched chain amino acids (BCAAs) modulate the development of the intra-cellular stages of Trypanosoma cruzi

LN Rapado, JF Nascimento, NC Manchola… - Experimental …, 2023 - Elsevier
The life cycle of Trypanosoma cruzi, the etiological agent of Chagas disease, involves different
forms of the parasite, which alternates between insect and vertebrate hosts. One critical …

Caracterização de dois homólogos da proteína de ligação ao CAP, EIF4E5 e 6, de Trypanossoma brucei e Leishmania major

JF Nascimento - 2012 - repositorio.ufpe.br
Os tripanossomatídeos são protozoários unicelulares que apresentam uma biologia
molecular bastante divergente dos demais eucariotos e são responsáveis por doenças …

Characterization of RBP9 and RBP10, two developmentally regulated RNA-binding proteins in $\textit {Trypanosoma brucei} $

LM De Pablos, S Kelly, J de Freitas Nascimento… - 2017 - repository.cam.ac.uk
The fate of an mRNA is determined by its interaction with proteins and small RNAs within
dynamic complexes called ribonucleoprotein complexes (mRNPs). In Trypanosoma brucei and …

[PDF][PDF] Fronteiras e pertenças: representações sociais e dinâmicas identitárias do tráfico de drogas na revista Veja (1968-2010)

…, IF Gianordoli-Nascimento… - Psicologia e Saber …, 2015 - researchgate.net
Este trabalho buscou compreender o processo de construção de representações sociais do
tráfico de drogas ao longo da história recente do país, acessando dinâmicas identitárias …

Representações sociais de “ser mulher militante”: as imbricações entre geração e gênero na trajetória de militância de mulheres durante a ditadura militar brasileira

IF Gianordoli-Nascimento… - … : Memória e história …, 2015 - periodicos.ufmg.br
Durante a ditadura militar (1964-1985), o Brasil presenciou um período de intensa repressão
política e social. Os grupos opositores ao regime eram compostos majoritariamente por …