White matter hyperintensities (WMHs) are frequently observed on structural neuroimaging
of elderly populations and are associated with cognitive decline and increased risk of …

The Ontario Neurodegenerative Research Initiative (ONDRI) is a 3 years multi-site
prospective cohort study that has acquired comprehensive multiple assessment platform data, …

Introduction Understanding synergies between neurodegenerative and cerebrovascular
pathologies that modify dementia presentation represents an important knowledge gap. …

Spontaneous variations in spinal cord activity may arise from regulation of any of a number
of functions including sensory, motor, and autonomic control. Here, we use functional MRI (…

Successful segmentation of the total intracranial vault (ICV) and ventricles is of critical importance
when studying neurodegeneration through neuroimaging. We present iCVMapper and …

Background Cerebral small vessel disease is associated with higher ratios of soluble‐epoxide
hydrolase derived linoleic acid diols (12,13‐dihydroxyoctadecenoic acid [DiHOME] and 9,…

Objective In individuals over the age of 65, concomitant neurodegenerative pathologies
contribute to cognitive and/or motor decline and can be aggravated by cerebrovascular disease, …

Quality assurance (QA) is crucial in longitudinal and/or multi-site studies, which involve the
collection of data from a group of subjects over time and/or at different locations. It is …

… Meek with a graduate studentship and Jane M. Lawrence-Dewar with a postdoctoral
research fellowship. Keri Locheed was supported by a Canadian Institutes of Health Research (…

Grouping local elements of the visual environment together is crucial for meaningful perception.
While our attentional system facilitates perception, it is limited in that we are unaware of …