A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
which is the causative agent of coronavirus disease 2019 (COVID-19), has …

Olfaction is a vitally important sense for all animals. There are striking similarities between
species in the organization of the olfactory pathway, from the nature of the odorant receptor …

Facioscapulohumeral dystrophy (FSHD) is one of the most common inherited muscular
dystrophies. The causative gene remains controversial and the mechanism of pathophysiology …

Human subtelomeres are polymorphic patchworks of interchromosomal segmental duplications
at the ends of chromosomes. Here we provide evidence that these patchworks arose …

We report a comprehensive comparative analysis of human and mouse olfactory receptor (OR)
genes. The OR family is the largest mammalian gene family known. We identify ∼93% of …

Olfactory receptor (OR) proteins interact with odorant molecules in the nose, initiating a
neuronal response that triggers the perception of a smell. The OR family is one of the largest …

Innate immune detection of nucleic acids is important for initiation of antiviral responses.
Detection of intracellular DNA activates STING-dependent type I interferons (IFNs) and the ASC-…

Post-translational protein modifications such as phosphorylation and ubiquitinylation are
common molecular targets of conflict between viruses and their hosts. However, the role of …

The V2R genes are expressed in the mammalian vomeronasal organ, and their products are
involved in detecting pheromones. Here, we describe the evolution of the V2R gene family. …

The human double-homeodomain retrogene DUX4 is expressed in the testis and epigenetically
repressed in somatic tissues. Facioscapulohumeral muscular dystrophy (FSHD) is …