Our lives revolve around sharing experiences and memories with others. When different
people recount the same events, how similar are their underlying neural representations? …

CRISPR-Cas12a (Cpf1) proteins are RNA-guided enzymes that bind and cut DNA as
components of bacterial adaptive immune systems. Like CRISPR-Cas9, Cas12a has been …

An outbreak of betacoronavirus severe acute respiratory syndrome (SARS)-CoV-2 began in
Wuhan, China in December 2019. COVID-19, the disease associated with SARS-CoV-2 …

The RNA-guided CRISPR–Cas9 nuclease from Streptococcus pyogenes (SpCas9) has
been widely repurposed for genome editing 1 , 2 , 3 , 4 . High-fidelity (SpCas9-HF1) and …

CRISPR-Cas systems provide microbes with adaptive immunity to infectious nucleic acids
and are widely employed as genome editing tools. These tools use RNA-guided Cas proteins …

Bacterial adaptive immunity and genome engineering involving the CRISPR (clustered regularly
interspaced short palindromic repeats)–associated (Cas) protein Cas9 begin with RNA-…

During realistic, continuous perception, humans automatically segment experiences into
discrete events. Using a novel model of cortical event dynamics, we investigate how cortical …

Models of working memory (WM) commonly focus on how information is encoded into and
retrieved from storage at specific moments. However, in the majority of real-life processes, …

Does the default mode network (DMN) reconfigure to encode information about the changing
environment? This question has proven difficult, because patterns of functional connectivity …

The control of IL-10 production and mechanisms that mediate synergy between IFN-γ and
TLR ligands are not well understood. We report that IFN-γ augments induction of TNFα by TLR …